The risk of endothelial and erectile dysfunctions in Behçet’s disease: a comparative analysis of mucocutaneous and systemic patient groups
| العنوان: | The risk of endothelial and erectile dysfunctions in Behçet’s disease: a comparative analysis of mucocutaneous and systemic patient groups |
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| المؤلفون: | Murat Kürtüncü, Ates Kadioglu, Huseyin Oflaz, Mehmet Barburoglu, Selcuk Erdem, Artur Salmaslioglu, Erkingül Shugaiv, Yasemin Erdem, Ekrem Bilal Karaayvaz, Afet Akdag Kose |
| المصدر: | Advances in Dermatology and Allergology, Vol 38, Iss 4, Pp 622-628 (2021) Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii |
| بيانات النشر: | Termedia Sp. z.o.o., 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, mucocutaneous, erectile dysfunction, Mucocutaneous zone, Population, Dermatology, Behcet's disease, Disease, behçet’s disease, Gastroenterology, endothelial dysfunction, Internal medicine, medicine, Immunology and Allergy, Endothelial dysfunction, systemic, education, Original Paper, education.field_of_study, business.industry, Coronary flow reserve, medicine.disease, RC31-1245, Increased risk, Erectile dysfunction, RL1-803, business |
| الوصف: | Introduction Behçet’s disease (BD) is a chronic inflammatory disease which can be limited to only mucocutaneous tissues or can affect different systems of the body. Aim To investigate the association of endothelial and erectile dysfunctions with BD, on the basis of comparative analysis between mucocutaneous and systemic BD. Material and methods Thirty-eight men diagnosed with BD were included in the present study. The patients were stratified into two groups as mucocutaneous BD (n = 20, MBD group), and systemic BD (n = 18, SBD group). Erectile dysfunction (ED) was assessed using the Erectile Function domain of the International Index of Erectile Function (IIEF-EF) questionnaire. The coronary flow reserve (CFR) assessment was done for analysing endothelial dysfunction (EnD), and CFR < 2 was defined as EnD. Penile Doppler ultrasonography (PDU) was performed for ED. The demographic and clinical parameters, IIEF-EF score ED classification, CFR and PDU test findings were compared between two groups. Results The median age was 34 (22–52) years in the overall population, and there was no difference between two groups (p = 0.558). Time from diagnosis was significantly longer (24 vs. 102 months, p = 0.021) and the use of immunosuppressive therapies was higher (0 vs. 70.6%, p < 0.001) in the SBD group. In overall, median CFR was 1.92 (1.1–5.96), and there was no difference between two groups (1.88 vs. 1.97, p = 0.812). The percentage of patients with CFR < 2 was similar in two groups (52.6% vs. 52.9%, p = 0.985). The ED status according to IIEF-EF was similar in two groups (45% vs. 27.8%, p = 0.538) as well as according to PDU analyses (10% vs. 16.7%, p = 0.544). Conclusions The increased risk of endothelial, and erectile dysfunctions should be considered in men who were diagnosed with mucocutaneous and systemic BD. |
| تدمد: | 1642-395X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e24b6fc36346b95cd0bd6f3c0693a10 https://doi.org/10.5114/ada.2021.108931 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....2e24b6fc36346b95cd0bd6f3c0693a10 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1642395X |
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