أعرض في EDS

Effects of preventive versus 'on-demand' nutritional support on paid labour productivity, physical exercise and performance status during PEG-interferon-containing treatment for hepatitis C

التفاصيل البيبلوغرافية
العنوان: Effects of preventive versus 'on-demand' nutritional support on paid labour productivity, physical exercise and performance status during PEG-interferon-containing treatment for hepatitis C
المؤلفون: Peter D. Siersema, Bart van Hoek, Karel J. van Erpecum, Joop E. Arends, Ellen J. Huisman, Karin M.J. van Nieuwkerk, Suzanne van Meer, Hanneke van Soest
المصدر: Clinics and Research in Hepatology and Gastroenterology, 40, 2, pp. 221-9
Clinics and Research in Hepatology and Gastroenterology, 40, 221-9
Clinics and Research in Hepatology and Gastroenterology, 40(2), 221-229
بيانات النشر: Elsevier BV, 2016.
سنة النشر: 2016
مصطلحات موضوعية: Male, medicine.medical_specialty, Evening, Physical exercise, Efficiency, Disease, Interferon alpha-2, Antiviral Agents, Polyethylene Glycols, law.invention, Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14], 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, On demand, Humans, Medicine, Prospective Studies, Karnofsky Performance Status, Exercise, Productivity, Hepatology, Performance status, Nutritional Support, business.industry, Gastroenterology, Interferon-alpha, Hepatitis C, Hepatitis C, Chronic, Middle Aged, medicine.disease, Recombinant Proteins, Nutrition Disorders, 030220 oncology & carcinogenesis, Physical therapy, Female, 030211 gastroenterology & hepatology, business
الوصف: Item does not contain fulltext BACKGROUND AND OBJECTIVE: Deterioration of nutritional status during PEG-interferon containing therapy for chronic hepatitis C can be ameliorated by preventive nutritional support. We aimed to explore whether such support also affects paid labour productivity, physical exercise and performance status. METHODS: In this prospective randomized controlled trial (J Hepatol 2012;57:1069-75), 53 patients with chronic hepatitis C had been allocated to "on demand" support (n=26: nutritional intervention if weight loss>5%) or preventive support (n=27: regular dietary advice plus energy- and protein-rich evening snack) during PEG-interferon-containing therapy. Paid labour productivity, physical exercise and performance status were evaluated at baseline, after 24 and (if applicable) after 48weeks of treatment. RESULTS: At baseline, 46% of patients performed paid labour and 62% performed some kind of physical exercise. Furthermore, most patients were able to carry out normal activity with only minor symptoms of disease (mean Karnofsky performance score: 94). Decreases of paid labour productivity (-21% vs. -70%, P=0.003), physical exercise activity (-43% vs. -87%, P=0.005) and Karnofsky performance scores (-12% vs. -24%, P
وصف الملف: application/pdf
تدمد: 2210-7401
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2edf035f11a4e726834d9f22bc09aba8
https://doi.org/10.1016/j.clinre.2015.06.007
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....2edf035f11a4e726834d9f22bc09aba8
قاعدة البيانات: OpenAIRE
الوصف
تدمد:22107401