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Change in microcalcifications on mammography after neoadjuvant chemotherapy in breast cancer patients: correlation with tumor response grade and comparison with lesion extent

التفاصيل البيبلوغرافية
العنوان: Change in microcalcifications on mammography after neoadjuvant chemotherapy in breast cancer patients: correlation with tumor response grade and comparison with lesion extent
المؤلفون: Yong Sik Jung, Taeyang Ha, Hyunee Yim, Doo Kyoung Kang, Seong Young Park, Tae Hee Kim
المصدر: Acta radiologica (Stockholm, Sweden : 1987). 60(2)
سنة النشر: 2018
مصطلحات موضوعية: medicine.medical_specialty, Neoplasm, Residual, medicine.medical_treatment, Breast Neoplasms, Tumor response, 030218 nuclear medicine & medical imaging, Lesion, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, medicine, Mammography, Humans, Radiology, Nuclear Medicine and imaging, Neoplasm Staging, Retrospective Studies, Chemotherapy, Radiological and Ultrasound Technology, medicine.diagnostic_test, business.industry, Calcinosis, Magnetic resonance imaging, General Medicine, Middle Aged, medicine.disease, Primary tumor, Magnetic Resonance Imaging, Neoadjuvant Therapy, Treatment Outcome, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Female, Radiology, medicine.symptom, Neoplasm Grading, business, Calcification
الوصف: Background After neoadjuvant chemotherapy (NAC), persistent microcalcifications are often observed in spite of a decrease in the primary tumor size. Purpose To analyze the changes in microcalcifications after NAC and to evaluate the accuracy of residual microcalcifications in predicting the extent of residual cancer. Material and Methods Eighty patients who received NAC and underwent both mammography and magnetic resonance imaging (MRI) before and after the completion of NAC were included. The location of microcalcifications was classified into two types: inside the mass and outside the mass. Results The extent of the residual calcifications was larger than the pathologic residual lesion in 14 (74%) of 19 patients with complete response (CR) on MRI, but the discrepancy was Conclusion The change in microcalcifications after NAC was correlated with the tumor response to NAC. The discrepancy was highest in the group showing CR on MRI with outside calcifications. In tumors with inside calcifications, the discrepancy was relatively low within an acceptable range.
تدمد: 1600-0455
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eecb0345c9187d3510b303698d5c5c4
https://pubmed.ncbi.nlm.nih.gov/29764199
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....2eecb0345c9187d3510b303698d5c5c4
قاعدة البيانات: OpenAIRE
الوصف
تدمد:16000455