Rheology of Polymethylmethacrylate-Collagen Gel Filler: Physiochemical Properties and Clinical Applications
| العنوان: | Rheology of Polymethylmethacrylate-Collagen Gel Filler: Physiochemical Properties and Clinical Applications |
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| المؤلفون: | Z Paul Lorenc, Tina McArthur, Brian Pilcher, Nimitt Patel |
| المصدر: | Aesthetic Surgery Journal. 41:NP88-NP93 |
| بيانات النشر: | Oxford University Press (OUP), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Rheometer, Cosmetic Techniques, engineering.material, 030207 dermatology & venereal diseases, 03 medical and health sciences, Viscosity, 0302 clinical medicine, Rheology, Filler (materials), Humans, Polymethyl Methacrylate, Medicine, Hyaluronic Acid, 030223 otorhinolaryngology, Elastic modulus, Rheometry, business.industry, General Medicine, Collagen gel, Durapatite, engineering, Surgery, Collagen, business, Calcium hydroxylapatite, Biomedical engineering |
| الوصف: | Background Soft tissue fillers are comprised of a range of materials with differing physiochemical and rheologic (ie, flow) properties. These properties can inform treatment selection for specific anatomic areas, planes of injection, and clinical applications. Objectives The aim of this study was to characterize the rheologic properties of polymethylmethacrylate (PMMA)-collagen gel for comparison with other available fillers. Methods Commercially available PMMA-collagen gel, hyaluronic acid (HA), and calcium hydroxylapatite (CaHA) fillers were obtained from their respective manufacturers. Measures of complex viscosity (η*) and elastic modulus (G′) for each filler were collected at 0.7 Hz in triplicate according to standard procedures on a rotational rheometer fitted with a 40-mm steel plate at 25°C on a Peltier plate (500-μm gap). Results The measured η* and G′ values for HA and CaHA fillers were in agreement with previously published data. The difference in η* between CaHA (mean [standard deviation], 358.9 [21.56] Pa-s) and PMMA-collagen gel (656.41 [68.03] Pa-s) was statistically significant (P < 0.0001), as was the difference between the G′ of CaHA (1424.8 [83.3] Pa) and the G′ of PMMA-collagen gel (2815.27 [304.07] Pa; P < 0.0001). Conclusions PMMA-collagen gel exhibited the highest η* and G′ of all tested fillers. These properties likely underpin an increased capacity for lifting and support in areas where long-lasting revolumization is appropriate. In practice, PMMA-collagen gel is well suited for treatment of acne scars, as well as injection into the supraperiosteal plane in the temple, chin, mandible, and piriform by a retrograde linear threading technique. Additional clinical considerations are discussed. |
| تدمد: | 1527-330X 1090-820X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f80343d4027c5f97fb8606f7085694f https://doi.org/10.1093/asj/sjaa314 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....2f80343d4027c5f97fb8606f7085694f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1527330X 1090820X |
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