Effects of hormone therapy on ambulatory blood pressure in postmenopausal Korean women
| العنوان: | Effects of hormone therapy on ambulatory blood pressure in postmenopausal Korean women |
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| المؤلفون: | Daeseon Choi, Koh Kk, Doh Kwan Kim, Dong-Yun Lee, Byung-Koo Yoon, Jwa-Jin Kim, Kim Jy |
| المصدر: | Climacteric. 14:92-99 |
| بيانات النشر: | Informa UK Limited, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | medicine.medical_specialty, Ambulatory blood pressure, Hormone Replacement Therapy, Systole, medicine.drug_class, medicine.medical_treatment, Urology, Diastole, Blood Pressure, Body Mass Index, Cohort Studies, Pregnancy, Internal medicine, Republic of Korea, medicine, Humans, Progesterone, Retrospective Studies, Estrogens, Conjugated (USP), business.industry, Obstetrics and Gynecology, Estrogens, Hormone replacement therapy (menopause), General Medicine, Blood Pressure Monitoring, Ambulatory, Middle Aged, medicine.disease, Circadian Rhythm, Postmenopause, Menopause, Parity, Endocrinology, Blood pressure, Estrogen, Hypertension, Ambulatory, Regression Analysis, Female, Progestins, business |
| الوصف: | Previous studies of the effects of postmenopausal hormone therapy (HT) on blood pressure have yielded inconsistent results.To examine the impact of HT on 24-h ambulatory blood pressure.A total of 67 postmenopausal Korean women (age 57.1 ± 5.7 years) received 2 months of HT consisting of conjugated equine estrogen (CEE, 0.625 mg/day) with or without micronized progesterone (100 mg/day). Ambulatory blood pressure monitoring was performed at baseline and after HT. Subjects were divided into those with normal blood pressure (n = 25) and those with high blood pressure (n = 42), based on their baseline daytime blood pressure.Parity and body mass index were higher in the group with high blood pressure than in the group with normal blood pressure. For both systolic and diastolic blood pressures throughout the day, significant negative correlations were observed between basal blood pressure and blood pressure difference after HT. During the daytime period, HT increased systolic and diastolic blood pressures in the subjects with normal blood pressure and decreased systolic and diastolic blood pressures in those with high blood pressure. When micronized progesterone was added to the CEE treatment, the increase in daytime blood pressure in the group with normal blood pressure was abolished, and the decrease in systolic blood pressure throughout the day in the group with high blood pressure was potentiated.HT had either blood pressure-elevating or blood pressure-lowering effects in postmenopausal Korean women, depending on basal blood pressure. CEE increased the daytime blood pressure in women with normal blood pressure, but reduced it in women with high blood pressure. Micronized progesterone may provide beneficial effects on blood pressure when combined with CEE. |
| تدمد: | 1473-0804 1369-7137 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310a3ad6ed8acc831fa246d37390762c https://doi.org/10.3109/13697137.2010.491924 |
| رقم الأكسشن: | edsair.doi.dedup.....310a3ad6ed8acc831fa246d37390762c |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 14730804 13697137 |
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