Detection of pure ground-glass nodules in the lung by low-dose multi-detector computed tomography, with use of an iterative reconstruction method: a comparison with conventional image reconstruction by the filtered back-projection method
التفاصيل البيبلوغرافية
العنوان:
Detection of pure ground-glass nodules in the lung by low-dose multi-detector computed tomography, with use of an iterative reconstruction method: a comparison with conventional image reconstruction by the filtered back-projection method
PURPOSE: To evaluate the feasibility of the iterative reconstruction (IR) method with low-dose multi-detector computed tomography (MDCT) for lung cancer screening. MATERIALS AND METHODS: A chest CT phantom containing simulated ground-glass nodules (GGNs) of 5 different sizes was scanned by use of 16-row and 64-row MDCT. Tube currents of 10, 20, and 30 mA were used for the low-dose CT. To assess the detectability of pure GGNs, a radiologist-performance test was conducted. Mean visual scores for simulated GGNs were compared for reconstructed images from filtered back-projection (FBP) and the IR method. RESULTS: When 64-row MDCT was used, visual scores for simulated GGNs were significantly higher for the IR method than for the FBP method under any conditions; scores were also significantly higher for 16-row MDCT under some conditions. CONCLUSIONS: The results of this experimental chest phantom study showed that use of the IR method improved the detectability of simulated pure GGNs.
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