Orbital medulloepithelioma in an adult patient: Radiation-induced second neoplasia?
| العنوان: | Orbital medulloepithelioma in an adult patient: Radiation-induced second neoplasia? |
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| المؤلفون: | Antony George Francis Thottian, Rony Benson, Seema Kashyap, Subhash Gupta, K.P. Haresh, Goura Kishor Rath, Dayanand Sharma |
| المصدر: | Orbit. 35:313-316 |
| بيانات النشر: | Informa UK Limited, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Pathology, Neoplasms, Radiation-Induced, Retinal Neoplasm, Retinal Neoplasms, Population, 03 medical and health sciences, 0302 clinical medicine, Germline mutation, Antineoplastic Combined Chemotherapy Protocols, Proton Therapy, medicine, Humans, Neuroectodermal Tumors, Primitive, education, education.field_of_study, Retinoblastoma, business.industry, Radiotherapy Planning, Computer-Assisted, Incidence (epidemiology), medicine.disease, Magnetic Resonance Imaging, Dermatology, eye diseases, Ophthalmology, 030220 oncology & carcinogenesis, Hereditary Retinoblastoma, 030221 ophthalmology & optometry, Second Malignancy, Orbital Neoplasms, Medulloepithelioma, Tomography, X-Ray Computed, business |
| الوصف: | Second cancers in survivors of hereditary retinoblastoma occur much more commonly than in the general population. This can be attributed both to the germline mutation of the RB gene and chemoradiation used for treatment of this paediatric cancer. Medulloepithelioma is an uncommon tumor of neuroectodermal origin, seen largely in the paediatric population and rarely reported in adults. Though the incidence of second malignancies is common in retinoblastoma, medulloepithelioma as a second malignancy in retinoblastoma survivors is rare, with only one case reported so far. Herein, we present a case of a 29-year-old patient presenting with medulloepithelioma of the right orbit, arising in the radiation field of previously treated retinoblastoma. This case was also peculiar in that though the origin of tumor was in the eyeball it had a very aggressive clinical course. |
| تدمد: | 1744-5108 0167-6830 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a0d51716af842218f5cb91d60858eb https://doi.org/10.1080/01676830.2016.1193536 |
| رقم الأكسشن: | edsair.doi.dedup.....33a0d51716af842218f5cb91d60858eb |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 17445108 01676830 |
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