ISA-TAB-Nano: a specification for sharing nanomaterial research data in spreadsheet-based format

التفاصيل البيبلوغرافية
العنوان: ISA-TAB-Nano: a specification for sharing nanomaterial research data in spreadsheet-based format
المؤلفون: Stacey L. Harper, Grace A. Stafford, Sharon Gaheen, David S. Paik, Martin Fritts, Elizabeth Hahn-Dantona, Juli Klemm, Elaine T. Freund, Dennis G. Thomas, Nathan A. Baker, Fred Klaessig, Sue Pan
المصدر: BMC Biotechnology
سنة النشر: 2012
مصطلحات موضوعية: 0303 health sciences, Standardization, business.industry, Information Dissemination, Research, Information Storage and Retrieval, 02 engineering and technology, Biology, Ontology (information science), 021001 nanoscience & nanotechnology, File format, Data type, Biotechnology, Nanostructures, Metadata, 03 medical and health sciences, Correspondence, State (computer science), 0210 nano-technology, Software engineering, business, Protocol (object-oriented programming), 030304 developmental biology
الوصف: Background and motivation The high-throughput genomics communities have been successfully using standardized spreadsheet-based formats to capture and share data within labs and among public repositories. The nanomedicine community has yet to adopt similar standards to share the diverse and multi-dimensional types of data (including metadata) pertaining to the description and characterization of nanomaterials. Owing to the lack of standardization in representing and sharing nanomaterial data, most of the data currently shared via publications and data resources are incomplete, poorly-integrated, and not suitable for meaningful interpretation and re-use of the data. Specifically, in its current state, data cannot be effectively utilized for the development of predictive models that will inform the rational design of nanomaterials. Results We have developed a specification called ISA-TAB-Nano, which comprises four spreadsheet-based file formats for representing and integrating various types of nanomaterial data. Three file formats (Investigation, Study, and Assay files) have been adapted from the established ISA-TAB specification; while the Material file format was developed de novo to more readily describe the complexity of nanomaterials and associated small molecules. In this paper, we have discussed the main features of each file format and how to use them for sharing nanomaterial descriptions and assay metadata. Conclusion The ISA-TAB-Nano file formats provide a general and flexible framework to record and integrate nanomaterial descriptions, assay data (metadata and endpoint measurements) and protocol information. Like ISA-TAB, ISA-TAB-Nano supports the use of ontology terms to promote standardized descriptions and to facilitate search and integration of the data. The ISA-TAB-Nano specification has been submitted as an ASTM work item to obtain community feedback and to provide a nanotechnology data-sharing standard for public development and adoption.
تدمد: 1472-6750
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357a129af54f581f27a8747ed6fd9e0f
https://pubmed.ncbi.nlm.nih.gov/23311978
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....357a129af54f581f27a8747ed6fd9e0f
قاعدة البيانات: OpenAIRE