Prospective randomized clinical trial of laparoscopic sleeve gastrectomy versus open Roux-en-Y gastric bypass for the management of patients with morbid obesity
| العنوان: | Prospective randomized clinical trial of laparoscopic sleeve gastrectomy versus open Roux-en-Y gastric bypass for the management of patients with morbid obesity |
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| المؤلفون: | Tadeusz Wróblewski, Mariusz Grodzicki, Zbigniew Bartoszewicz, Piotr Kalinowski, Janina Białobrzeska-Paluszkiewicz, Piotr Remiszewski, Bogna Ziarkiewicz-Wróblewska, Marek Krawczyk, Rafał Paluszkiewicz |
| المصدر: | Videosurgery and other Miniinvasive Techniques |
| بيانات النشر: | Termedia Publishing House, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Sleeve gastrectomy, medicine.medical_specialty, Urology, medicine.medical_treatment, bariatric surgery, Gastric bypass, law.invention, Morbid obesity, Randomized controlled trial, Weight loss, law, medicine, randomized trial, gastric bypass, Original Paper, business.industry, Gold standard, Gastroenterology, Obstetrics and Gynecology, nutritional and metabolic diseases, Roux-en-Y anastomosis, Surgery, morbid obesity, medicine.symptom, business, Body mass index, sleeve gastrectomy |
| الوصف: | Introduction: Roux-en-Y gastric bypass (RYGB) is considered the gold standard bariatric procedure with documented safety and effectiveness. Laparoscopic sleeve gastrectomy (LSG) is a newer procedure being done with increasing fre - quency. Randomized comparisons of LSG and other bariatric procedures are limited. We present the results of the first prospective randomized trial comparing LSG and RYGB in the Polish population. Aim: To assess the efficacy and safety of LSG versus RYGB in the treatment of morbid obesity and obesity-related comorbidities. Material and methods: Seventy-two morbidly obese patients were randomized to RYGB (36 patients) or LSG (36 patients). Both groups were comparable regarding age, gender, body mass index (BMI) and comorbidities. The fol - low-up period was at least 12 months. Baseline and 6 and 12 month outcomes were analyzed including assessment of percent excess weight lost (%EWL), reduction in BMI, morbidity (minor, major, early and late complications), mor - tality, reoperations, comorbidities and nutritional deficiencies. Results: There was no 30-day mortality and no significant difference in major complication rate (0% after RYGB and 8.3% after LSG, p > 0.05) or minor complication rate (16.6% after RYGB and 10.1% after LSG, p > 0.05). There were no early reoperations after RYGB and 2 after LSG (5.5%) (p > 0.05). Weight loss was significant after RYGB and LSG but there was no difference between both groups at 6 and 12 months of follow-up. At 12 months %EWL in RYGB and LSG groups reached 64.2% and 67.6% respectively (p > 0.05). There was no significant difference in the overall prevalence of comorbidities and nutritional deficiencies. Conclusions: Both LSG and RYGB produce significant weight loss at 6 and 12 months after surgery. The procedures are equally effective with regard to %EWL, reduction in BMI and amelioration of comorbidities at 6 and 12 months of fol - low-up. Laparoscopic sleeve gastrectomy and RYGB are comparably safe techniques with no significant differences in minor and major complication rates at 6 and 12 months. |
| اللغة: | English |
| تدمد: | 2299-0054 1895-4588 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3633f2a262d54033bf455ed211ffb575 http://europepmc.org/articles/PMC3557743 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....3633f2a262d54033bf455ed211ffb575 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22990054 18954588 |
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