Hijacking a Linaridin Biosynthetic Intermediate for Lanthipeptide Production
| العنوان: | Hijacking a Linaridin Biosynthetic Intermediate for Lanthipeptide Production |
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| المؤلفون: | Leixia Chu, Jinduo Cheng, Chengzeng Zhou, Tianlu Mo, Xinjian Ji, Taoting Zhu, Jie Chen, Suze Ma, Jiangtao Gao, Qi Zhang |
| المصدر: | ACS Chemical Biology. 17:3198-3206 |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Biological Products, Multigene Family, Molecular Medicine, Amino Acid Sequence, Cysteine, General Medicine, Peptides, Protein Processing, Post-Translational, Biochemistry |
| الوصف: | Linaridins and lanthipeptides are two classes of natural products belonging to the ribosomally synthesized and posttranslationally modified peptide (RiPP) superfamily. Although these two RiPP classes share similar structural motifs such as dehydroamino acids and thioether-based cross-links, the biosynthesis of linaridins and lanthipeptides involved distinct sets of enzymes. Here, we report the identification of a novel lanthipeptide cypepeptin from a recombinant strain of |
| تدمد: | 1554-8937 1554-8929 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363ce2983b7499f12a202c70617f1cd0 https://doi.org/10.1021/acschembio.2c00657 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....363ce2983b7499f12a202c70617f1cd0 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15548937 15548929 |
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