Duffy Blood Types and Vivax Malaria in Ethiopia *
| العنوان: | Duffy Blood Types and Vivax Malaria in Ethiopia * |
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| المؤلفون: | H. M. Mathews, J. C. Armstrong |
| المصدر: | The American Journal of Tropical Medicine and Hygiene. 30:299-303 |
| بيانات النشر: | American Society of Tropical Medicine and Hygiene, 1981. |
| سنة النشر: | 1981 |
| مصطلحات موضوعية: | Adult, Male, Study groups, Veterinary medicine, Adolescent, Population, Plasmodium vivax, Virology, parasitic diseases, Genotype, medicine, Humans, Child, education, Demography, education.field_of_study, biology, business.industry, Racial Groups, medicine.disease, biology.organism_classification, Malaria, West african, Infectious Diseases, Child, Preschool, Vivax malaria, Blood Group Antigens, Female, Parasitology, Ethiopia, Duffy Blood-Group System, business |
| الوصف: | We investigated an hypothesis relating the Duffy-negative blood type with insusceptibility to vivax malaria—and previously associated only with people of West African ancestry—in three population samples of eastern African stock. The samples included Nilotic and Hamitic-Semitic residents of a malarious locale in Ethiopia and Hamito-Semites in Addis Ababa where malaria is not endemic. Fresh red blood cells from 191 subjects were tested with Duffy antisera, anti-Fya and anti-Fyb. Duffy-positive rates in the malarious community were 8% for the Nilotes and 70% for the Hamito-Semites; the Hamito-Semites in Addis Ababa were 98% Duffy-positive. The relative prevalences of Plasmodium vivax in the two study groups at risk to malaria were 2.4% for the Nilotes and 27.3% for the Hamito-Semites, producing a ratio similar to the ratio of Duffy-positives in the two samples. We interpret the data as supportive of the Duffy-vivax hypothesis with reference to a part of eastern Africa, and we suggest that the Duffy-negative genotype may represent the original, rather than the mutant, condition in tropical Africa. |
| تدمد: | 1476-1645 0002-9637 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365e6415a66acd9923d5ab9aa832d40f https://doi.org/10.4269/ajtmh.1981.30.299 |
| رقم الأكسشن: | edsair.doi.dedup.....365e6415a66acd9923d5ab9aa832d40f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14761645 00029637 |
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