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Intensive prolonged exposure therapy for chronic PTSD patients following multiple trauma and multiple treatment attempts

التفاصيل البيبلوغرافية
العنوان: Intensive prolonged exposure therapy for chronic PTSD patients following multiple trauma and multiple treatment attempts
المؤلفون: Agnes van Minnen, Gert-Jan Hendriks, Rianne A. de Kleine, Lotte Hendriks, T. G. Broekman
المصدر: European Journal of Psychotraumatology, 9, 1, pp.
European journal of psychotraumatology, 9(1), 1-15
European Journal of Psychotraumatology
European Journal of Psychotraumatology, 9,
European Journal of Psychotraumatology, Vol 9, Iss 1 (2018)
European journal of psychotraumatology
سنة النشر: 2018
مصطلحات موضوعية: 强化治疗, 050103 clinical psychology, medicine.medical_specialty, lcsh:RC435-571, medicine.medical_treatment, Treatment outcome, Exposure therapy, Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13], Complex ptsd, behavioral disciplines and activities, (complex) PTSD, Experimental Psychopathology and Treatment, 03 medical and health sciences, 0302 clinical medicine, All institutes and research themes of the Radboud University Medical Center, lcsh:Psychiatry, TEPT (complejo), mental disorders, Medicine, 0501 psychology and cognitive sciences, • Current trauma-focused treatment (TFT), including prolonged exposure (PE), usually lasts several months with sessions being delivered on a weekly basis.• In this study, PE is administered in an accelerated way in chronic PTSD patients with a likely diagnosis of ICD-11 Complex PTSD following multiple interpersonal trauma and a history of multiple treatment attempts.• The results of this open study suggest that intensive PE (iPE) can be effective. Although previous treatment attempts were unsuccessful in these patients, 71% showed partial or complete response during iPE. In addition, iPE was found to be safe and dropout rates were very low, Dropout (neural networks), response patterns, tratamiento intensivo, Clinical Research Article, Prolonged exposure therapy, predictores, patrones de respuesta, business.industry, 反应模式, Intensive treatment, resultado del tratamiento, 05 social sciences, 治疗结果, （复杂）PTSD, (prolonged) exposure, intensive treatment, 030227 psychiatry, Prolonged exposure, （延长）暴露, Posttraumatic stress, predictors, Emergency medicine, treatment outcome, business, exposición (prolongada), 预测指标, Research Article
الوصف: Background: Suboptimal response and high dropout rates leave room for improvement of trauma-focused treatment (TFT) effectiveness in ameliorating posttraumatic stress disorder (PTSD) symptoms. Objective: To explore the effectiveness and safety of intensive prolonged exposure (iPE) targeting chronic PTSD patients with a likely diagnosis of ICD-11 Complex PTSD following multiple interpersonal trauma and a history of multiple treatment attempts. Method: Participants (N = 73) received iPE in 12 × 90-minute sessions over four days (intensive phase) followed by four weekly 90-minute booster prolonged exposure (PE) sessions (booster phase). The primary outcomes, clinician-rated severity of PTSD symptoms, and diagnostic status (Clinician-Administered PTSD Scale; CAPS-IV) were assessed at baseline, post-treatment, and at three and six months. Treatment response trajectories were identified and predictors of these trajectories explored. Results: Mixed model repeated measures analysis of CAPS-IV scores showed a baseline-to-posttreatment decrease in PTSD symptom severity (p < .001) that persisted during the three- and six-month follow-ups with large effect sizes (Cohen’s d > 1.2); 71% of the participants responded. None of the participants dropped out during the intensive phase and only 5% during the booster phase. Adverse events were extremely low and only a minority showed symptom exacerbation. Cluster analysis demonstrated four treatment response trajectories: Fast responders (13%), Slow responders (26%), Partial responders (32%), and Non-responders (29%). Living condition and between-session fear habituation were found to predict outcome. Participants living alone were more likely to belong to the Partial responders than to the Non-responders cluster, and participants showing more between-session fear habituation were more likely to belong to the Fast responders than to the Non-responders cluster. Conclusions: The results of this open study suggest that iPE can be effective in PTSD patients with multiple interpersonal trauma and after multiple previous treatment attempts. In addition, in this chronic PTSD population iPE was safe.
وصف الملف: application/pdf
تدمد: 2000-8198
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d7adaaea7aa0caba6f8ddf8a1ac8e6
https://hdl.handle.net/2066/185908
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....36d7adaaea7aa0caba6f8ddf8a1ac8e6
قاعدة البيانات: OpenAIRE
الوصف
تدمد:20008198