Mutations of TP53 gene in adult acute lymphoblastic leukemia at diagnosis do not affect the achievement of hematologic response but correlate with early relapse and very poor survival
| العنوان: | Mutations of TP53 gene in adult acute lymphoblastic leukemia at diagnosis do not affect the achievement of hematologic response but correlate with early relapse and very poor survival |
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| المؤلفون: | Barbara Peruta, Tamara Intermesoli, Emanuele Angelucci, Elisabetta Terruzzi, Orietta Spinelli, Silvia Salmoiraghi, Alessandro Rambaldi, Manuela Tosi, Pamela Zanghì, Greta Ubiali, Elena Oldani, Irene Cavattoni, Cristina Boschini, Fabio Ciceri, Alexander Kohlmann, Silvia Bungaro, Renato Bassan, Marie Lorena Guinea Montalvo |
| المساهمون: | Salmoiraghi, Silvia, Montalvo, Marie Lorena Guinea, Ubiali, Greta, Tosi, Manuela, Peruta, Barbara, Zanghi, Pamela, Oldani, Elena, Boschini, Cristina, Kohlmann, Alexander, Bungaro, Silvia, Intermesoli, Tamara, Terruzzi, Elisabetta, Angelucci, Emanuele, Cavattoni, Irene, Ciceri, Fabio, Bassan, Renato, Rambaldi, Alessandro, Spinelli, Orietta |
| المصدر: | Haematologica. 101:e245-e248 |
| بيانات النشر: | Ferrata Storti Foundation (Haematologica), 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Adult, Male, Oncology, medicine.medical_specialty, Survival, Early Relapse, Acute lymphoblastic leukemia, Affect (psychology), medicine.disease_cause, Tp53 mutation, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Internal medicine, medicine, Humans, Online Only Articles, Survival rate, Gene, Mutation, business.industry, TP53 mutation, Hematology, Middle Aged, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Hematologic Response, Survival Rate, 030220 oncology & carcinogenesis, Immunology, Adult Acute Lymphoblastic Leukemia, Female, Early relapse, Tumor Suppressor Protein p53, business, Human, 030215 immunology |
| الوصف: | In adult acute lymphoblastic leukemia (ALL) the evaluation of clinical and biological conventional risk criteria at diagnosis is important but not sufficient to predict clinical outcome. The impact of TP53 mutations has been investigated in a limited number of studies and has still not been defined |
| تدمد: | 1592-8721 0390-6078 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f38e28c2bf2bd6ae8f357cee3c9312 https://doi.org/10.3324/haematol.2015.137059 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....36f38e28c2bf2bd6ae8f357cee3c9312 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15928721 03906078 |
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