Serum cystatin C is an easy to obtain biomarker for the onset of renal impairment in heart transplant recipients

التفاصيل البيبلوغرافية
العنوان: Serum cystatin C is an easy to obtain biomarker for the onset of renal impairment in heart transplant recipients
المؤلفون: Gerhard Wirnsberger, Andrä Wasler, Florian Iberer, Daniela Kniepeiss, Karlheinz Tscheliessnigg, Doris Wagner, Regina E. Roller
المصدر: The Journal of Thoracic and Cardiovascular Surgery. 140:688-693
بيانات النشر: Elsevier BV, 2010.
سنة النشر: 2010
مصطلحات موضوعية: Male, Hypertension, Renal, Time Factors, medicine.medical_treatment, urologic and male genital diseases, chemistry.chemical_compound, Risk Factors, Medicine, Prospective Studies, Renal Insufficiency, Heart transplantation, Kidney, biology, Middle Aged, Treatment Outcome, medicine.anatomical_structure, Austria, Creatinine, Biomarker (medicine), Drug Therapy, Combination, Female, Cardiology and Cardiovascular Medicine, Immunosuppressive Agents, Glomerular Filtration Rate, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Urology, Renal function, Risk Assessment, Predictive Value of Tests, Humans, Cystatin C, Aged, business.industry, medicine.disease, Surgery, Transplantation, Early Diagnosis, Logistic Models, ROC Curve, chemistry, biology.protein, Heart Transplantation, business, Biomarkers, Follow-Up Studies, Kidney disease
الوصف: ObjectiveWith the increasing longevity of heart transplant recipients, the long-term effects of cyclosporine on renal function have become more evident. Highly sensitive, early, and effective monitoring of posttransplant renal function is still being researched. This study aimed to evaluate the prognostic value of cystatin C for patients after heart transplantation.MethodsSeventy-three long-term recipients of a heart transplant more than 5 years before the study start were included in the analysis with a follow-up of 4 years. Serum creatinine, renal glomerular filtration rate calculated by the Modification of Diet in Renal Disease formula, and serum cystatin C levels were collected, and risk factors for renal dysfunction were assessed. Statistical analysis was performed for all patients.ResultsUnivariate analysis showed a prognostic impact of antihypertensive medication and onset of diabetes (P
تدمد: 0022-5223
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3708df7ca3f38445965d941193cd8919
https://doi.org/10.1016/j.jtcvs.2010.03.031
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....3708df7ca3f38445965d941193cd8919
قاعدة البيانات: OpenAIRE