Mindfulness‐based cognitive therapy in functional dyspepsia: A pilot randomized trial
| العنوان: | Mindfulness‐based cognitive therapy in functional dyspepsia: A pilot randomized trial |
|---|---|
| المؤلفون: | Webber Chan, Steven Mesenas, Kinjal Doshi, Ying Hao, Yi-Kang Ng, Lui-Yee Ang, Kevin Kim-Jun Teh, Andrew Ming Liang Ong, Shu-Wen Tay, Kewin Tien Ho Siah, Henry Lew-Yuen Foong, Chee-Hooi Lim, Wai-Choung Ong, Yu-Tien Wang |
| المصدر: | Journal of Gastroenterology and Hepatology. 36:2058-2066 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Mindfulness, Randomization, medicine.medical_treatment, Psychological intervention, Pilot Projects, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, medicine, Humans, Dyspepsia, Mindfulness-based cognitive therapy, Cognitive Behavioral Therapy, Hepatology, business.industry, Gastroenterology, Cognitive behavioral therapy, Treatment Outcome, 030220 oncology & carcinogenesis, Psychotherapy, Group, Cognitive therapy, Physical therapy, Anxiety, 030211 gastroenterology & hepatology, medicine.symptom, business |
| الوصف: | Background and aim Patients with functional dyspepsia (FD) often have concomitant anxiety and depression. Mindfulness-based cognitive therapy (MBCT) combines the principles of cognitive behavioral therapy and mindfulness. It is a group-based therapy and has been shown to be efficacious in functional gastrointestinal disorders. There are no randomized controlled trials (RCTs) evaluating MBCT in FD. We aimed to evaluate feasibility and efficacy of MBCT in FD management. Methods We performed a mixed-method single-center pilot randomized trial of 28 patients fulfilling ROME-III criteria for FD. Fifteen patients were randomized to an 8-week MBCT program while 13 underwent treatment-as-usual (TAU). Patients completed questionnaires at baseline and at week 8. Two focus-groups were conducted. Feasibility of recruitment, acceptability of randomization, procedures and intervention, handout compliance and feasibility of quantitative measures were assessed. The primary outcome was subjective-clinical-assessment of FD symptoms (SCA-FD). Secondary outcome measures included Short-form Nepean Dyspepsia Index (SF-NDI), subjective-clinical-assessment of general health (SCA-GH), EuroQoL-Visual Analog Scale (EuroQoL-VAS), and Depression, Anxiety and Stress Scale-21 Items (DASS-21). Results Twelve of 15 patients in the MBCT group completed the program. There was a trend towards symptom improvement, with 90% in the MBCT group reporting improvement in SCA-FD compared with 45% in TAU(P = 0.063). Patients who underwent MBCT reported greater improvement in SF-NDI (mean change: -8.8 (SD: 7.5) vs -0.7 (7.2), P = 0.018) and DASS-21 (-19.8 (29.5) vs -5.5 (6.6) P = 0.13) compared with TAU. There was no difference in SCA-GH and EuroQoL-VAS. Based on SCA-FD improvement, the eventual RCT will require 50 patients (25 in each group). Conclusions Mindfulness-based cognitive therapy is likely efficacious for FD, and it would be feasible to conduct a RCT. |
| تدمد: | 1440-1746 0815-9319 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3739da70345f3bd899bd4b979b42dd1b https://doi.org/10.1111/jgh.15389 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....3739da70345f3bd899bd4b979b42dd1b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14401746 08159319 |
|---|