The impact of fluticasone furoate/vilanterol on healthcare resource utilisation in the Salford Lung Study in chronic obstructive pulmonary disease
| العنوان: | The impact of fluticasone furoate/vilanterol on healthcare resource utilisation in the Salford Lung Study in chronic obstructive pulmonary disease |
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| المؤلفون: | Jodie Crawford, Isabelle Boucot, John P. New, D. Browning, Nawar Diar Bakerly, Norman Stein, Sheila McCorkindale |
| المصدر: | Therapeutic Advances in Respiratory Disease, Vol 15 (2021) Bakerly, N D, Browning, D, Boucot, I, Crawford, J, McCorkindale, S, Stein, N & New, J P 2021, ' The impact of fluticasone furoate/vilanterol on healthcare resource utilisation in the Salford Lung Study in chronic obstructive pulmonary disease ', Therapeutic Advances in Respiratory Disease, vol. 15 . https://doi.org/10.1177/17534666211001013 Therapeutic Advances in Respiratory Disease Bakerly, N D, Browning, D, Boucot, I, Crawford, J, McCorkindale, S, Stein, N & New, J P 2021, ' The impact of fluticasone furoate/vilanterol on healthcare resource utilisation in the Salford Lung Study in chronic obstructive pulmonary disease ', Therapeutic Advances in Respiratory Disease, vol. 15, pp. 17534666211001013 . https://doi.org/10.1177/17534666211001013 |
| بيانات النشر: | SAGE Publishing, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, law.invention, chemistry.chemical_compound, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Randomized controlled trial, law, healthcare resource utilisation, Health care, Electronic Health Records, Pharmacology (medical), 030212 general & internal medicine, Prospective Studies, Original Research, Aged, 80 and over, COPD, fluticasone furoate, vilanterol, Health Care Costs, Middle Aged, Hospitalization, Drug Combinations, medicine.anatomical_structure, Female, Vilanterol, medicine.drug, Adult, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Pulmonary disease, effectiveness, Chlorobenzenes, Fluticasone propionate, 03 medical and health sciences, usual care, medicine, Humans, Intensive care medicine, Benzyl Alcohols, Aged, lcsh:RC705-779, Lung, business.industry, lcsh:Diseases of the respiratory system, Length of Stay, Patient Acceptance of Health Care, medicine.disease, Fluticasone furoate/vilanterol, Androstadienes, 030228 respiratory system, chemistry, business |
| الوصف: | Aim: The Salford Lung Study (SLS) in chronic obstructive pulmonary disease (COPD) was a randomised controlled trial evaluating the effectiveness and safety of initiating fluticasone furoate/vilanterol (FF/VI) 100/25 µg versus continuing usual care (UC) in patients with COPD and a history of exacerbations. Here, we investigate the impact of initiating FF/VI on healthcare resource utilisation (HRU) in SLS COPD. Methods: HRU and interventions were determined from patients’ electronic health records. Annual rates of on-treatment all-cause and COPD-related secondary care contacts (SCCs) and primary care contacts (PCCs) for FF/VI versus UC were analysed using a general linear model. Costs were derived from national data sources. Results: Least-squares (LS) mean annual rates of all-cause (9.81 versus 9.36) and COPD-related (1.57 versus 1.48) SCCs were similar for FF/VI and UC, as were rates of all-cause hospitalisations (0.87 versus 0.82). Mean duration of hospital stay/patient was 4.5 and 4.2 days, respectively. COPD-related SCC mean total cost/patient was £484 FF/VI and £475 UC. LS mean annual rates of all-cause PCCs were significantly higher for FF/VI (21.20 versus 18.88 UC; p Discussion: In patients with COPD and exacerbation history, FF/VI may represent a less costly alternative to current therapies. GlaxoSmithKline plc. study HZC115151; ClinicalTrials.gov NCT01551758. The reviews of this paper are available via the supplemental material section. |
| اللغة: | English |
| تدمد: | 1753-4666 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385254c675475c1a006c8c614149b8be https://doaj.org/article/0e25fbfa22b84f6da3da18c66da22f71 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....385254c675475c1a006c8c614149b8be |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17534666 |
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