Odynophagia as the first manifestation of toxic epidermal necrolysis

التفاصيل البيبلوغرافية
العنوان: Odynophagia as the first manifestation of toxic epidermal necrolysis
المؤلفون: Noelia Ortega Beltrá, Fernando Guallart Domenech, Paula Martínez Ruiz de Apodaca, Francisco Pons Rocher
المصدر: BMJ Case Reports. 15:e250305
بيانات النشر: BMJ, 2022.
سنة النشر: 2022
مصطلحات موضوعية: Male, Stevens-Johnson Syndrome, Acute Disease, Humans, Pain, Sulfadiazine, General Medicine, Deglutition Disorders
الوصف: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are infrequent mucocutaneous diseases, rapidly progressive and life-threatening. The clinical aspects and the management of TEN are exposed following a case.A man in his 40s presented to the emergency department with severe odynophagia, poor general condition and fever. His medical history was significant for HIV stage AIDS, and the treatment was discontinued 5 years before the present diagnosis. He was admitted for cerebral toxoplasmosis and discharged the previous 14 days with sulfadiazine. Erythematous-bullous lesions in the oral cavity, diffuse erythematous maculopapular rashes over his neck and chest, acute bilateral conjunctivitis and purulent urethritis was observed. The diagnostic suspicion was SJS/TEN due to sulfadiazine in immunosuppressed patients.This entity is infrequent but is a life-threatening dermatological emergency that requires immediate medical attention. Its diagnosis is mainly clinical, with a new drug history, prodromal symptoms and characteristic cutaneous–mucous lesions. Early diagnosis and rapid withdrawal of the drug improve the prognosis.
تدمد: 1757-790X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388e21e102291d23acda4302db9ca177
https://doi.org/10.1136/bcr-2022-250305
رقم الأكسشن: edsair.doi.dedup.....388e21e102291d23acda4302db9ca177
قاعدة البيانات: OpenAIRE