Clinical characteristics of COVID‐19 patients evaluated in the emergency department: A retrospective cohort study of 801 cases
| العنوان: | Clinical characteristics of COVID‐19 patients evaluated in the emergency department: A retrospective cohort study of 801 cases |
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| المؤلفون: | Mary E. Reed, Ian D McLachlan, Dustin W. Ballard, Adina S. Rauchwerger, Sean C Bouvet, Liyan Liu, David R. Vinson, Dale M Cotton, Dana R. Sax, Mamata V. Kene, Scott D. Casey, Edward J. Durant, Judy Shan, Meena Ghiya, Erik R. Hofmann, James S. Lin, Dustin G. Mark |
| المصدر: | Journal of the American College of Emergency Physicians Open, Vol 2, Iss 4, Pp n/a-n/a (2021) Journal of the American College of Emergency Physicians Open Journal of the American College of Emergency Physicians open, vol 2, iss 4 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Respiratory rate, Vital signs, Clinical Research on Emergency Services and Treatment (CREST) Network, Infectious Disease, Disease, medicine.disease_cause, Clinical Research, COVID‐19, Internal medicine, medicine, Neutrophil to lymphocyte ratio, Lung, Original Research, Pediatric, medicine.diagnostic_test, business.industry, emergency, RC86-88.9, COVID-19, critical characteristics, Retrospective cohort study, Medical emergencies. Critical care. Intensive care. First aid, Emergency department, Auscultation, Health Services, Infectious Diseases, Emerging Infectious Diseases, business, Nasal cannula, hospitalization |
| الوصف: | Background Coronavirus disease 2019 (COVID‐19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has extracted devastating tolls. Despite its pervasiveness, robust information on disease characteristics in the emergency department (ED) and how that information predicts clinical course remain limited. Methods We conducted a retrospective cohort study of the first ED visit from SARS‐CoV‐2‐positive patients in our health system, from February 21, 2020 to April 5, 2020. We reviewed each patient's ED visit(s) and included the first visit with symptoms consistent with COVID‐19. We collected demographic, clinical, and treatment variables from electronic health records and structured manual chart review. We used multivariable logistic regression to examine the association between patient characteristics and 2 primary outcomes: a critical outcome and hospitalization from index visit. Our critical outcome was defined as death or advanced respiratory support (high flow nasal cannula or greater) within 21 days. Results Of the first 1030 encounters, 801 met our inclusion criteria: 15% were over age 75 years, 47% were female, and 24% were non‐Hispanic white. We found 161 (20%) had a critical outcome and 393 (49%) were hospitalized. Independent predictors of a critical outcome included a history of hypertension, abnormal chest x‐ray, elevated neutrophil to lymphocyte ratio, elevated blood urea nitrogen (BUN), measured fever, and abnormal respiratory vital signs (respiratory rate, oxygen saturation). Independent predictors of hospitalization included abnormal pulmonary auscultation, elevated BUN, measured fever, and abnormal respiratory vital signs. Conclusions In this large, diverse study of ED patients with COVID‐19, we have identified numerous clinical characteristics that have independent associations with critical illness and hospitalization. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2688-1152 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391802544961d7a1ad1bbbdc66006947 https://doaj.org/article/18406c4121c447b7a80137cb2d1b22c9 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....391802544961d7a1ad1bbbdc66006947 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 26881152 |
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