Clinical application of interventional renal sympathetic denervation: recommendations of the Austrian Society of Hypertension 2012
العنوان: | Clinical application of interventional renal sympathetic denervation: recommendations of the Austrian Society of Hypertension 2012 |
---|---|
المؤلفون: | Katharina Hohenstein, Johann Auer, Helmut Brussee, Thomas Lambert, Peter Grüner, Bruno Watschinger, Jörg H. Horina, Thomas Weber, Mathias C. Brandt, Uta C. Hoppe, Robert Zweiker, Christian Koppelstätter |
المصدر: | Wiener klinische Wochenschrift. 124:789-798 |
بيانات النشر: | Springer Science and Business Media LLC, 2012. |
سنة النشر: | 2012 |
مصطلحات موضوعية: | medicine.medical_specialty, Sympathetic nervous system, Hypertension, Renal, Percutaneous, business.industry, General Medicine, Kidney, Pathophysiology, Clinical trial, Blood pressure, medicine.anatomical_structure, Renal sympathetic denervation, Austria, Internal medicine, Adventitia, Practice Guidelines as Topic, Cardiology, Humans, Medicine, Sympathectomy, business, Intensive care medicine, Adverse effect |
الوصف: | Increased activity of the sympathetic nervous system plays a major role in the pathophysiology of primary arterial hypertension. Interventional renal sympathetic denervation (RSD) is a novel percutaneous treatment, decreasing sympathetic activity and consecutively blood pressure by ablating sympathetic nervous fibers located in the adventitia of the renal arteries. The procedure has been tested in several clinical trials in patients with resistant hypertension (defined as systolic office blood pressure > 160 mmHg—in diabetic patients > 150 mmHg—treated with ³ 3 antihypertensive drugs) and caused a meaningful blood pressure reduction, lasting for at least 3 years. So far, no major adverse events have been identified; however, data on the long-term consequences are lacking. The present position paper of the Austrian Society of Hypertension is aiming to assist in choosing possible indications for RSD in clinical routine, based on the available evidence in 2012. |
تدمد: | 1613-7671 0043-5325 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398ab1aae3b56c1f54cb79f6a638207b https://doi.org/10.1007/s00508-012-0257-3 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi.dedup.....398ab1aae3b56c1f54cb79f6a638207b |
قاعدة البيانات: | OpenAIRE |
تدمد: | 16137671 00435325 |
---|