التفاصيل البيبلوغرافية
العنوان:
Evaluation of Time to Detection of Mycobacterium tuberculosis in Broth Culture as a Determinant for End Points in Treatment Trials▿ †
المؤلفون:
Grace Muzanye , Thomas J. Prihoda , Melissa Engle , Marc H Weiner , John L. Johnson , A. Willem Sturm , Nesri Padayatchi , Stefan V. Goldberg , Roy D. Mugerwa , Paula A. Duran , William J. Burman
بيانات النشر:
American Society for Microbiology (ASM), 2010.
سنة النشر:
2010
مصطلحات موضوعية:
Microbiology (medical) , Adult , Male , medicine.medical_specialty , Tuberculosis , Time Factors , Moxifloxacin , Antitubercular Agents , Gastroenterology , Treatment failure , Mycobacterium tuberculosis , Pharmacotherapy , Internal medicine , Medicine , Humans , A determinant , Aza Compounds , Bacteriological Techniques , Clinical Trials as Topic , Time to detection , Lung , biology , business.industry , Mycobacteriology and Aerobic Actinomycetes , Middle Aged , biology.organism_classification , medicine.disease , Treatment efficacy , medicine.anatomical_structure , Immunology , Quinolines , Female , Drug Monitoring , business , Ethambutol , Fluoroquinolones
الوصف:
Time to detection of Mycobacterium tuberculosis in broth culture was examined for utility as a treatment efficacy end point. Of 146 patients in a phase IIB trial, a decreased mean time to detection was found in 5 with treatment failure. Time to detection in an analysis-of-covariance model was associated with lung cavities, less intensive treatment, and differences in the bactericidal effects of treatment regimens.
اللغة:
English
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3993da54bcbead29b71fa3ad81524b96 https://europepmc.org/articles/PMC3008491 /
حقوق:
OPEN
رقم الأكسشن:
edsair.doi.dedup.....3993da54bcbead29b71fa3ad81524b96
قاعدة البيانات:
OpenAIRE
