Phases of myogenic cell activation and possible role of dermomyotome cells in teleost muscle formation
| العنوان: | Phases of myogenic cell activation and possible role of dermomyotome cells in teleost muscle formation |
|---|---|
| المؤلفون: | Walter Stoiber, Peter Steinbacher, M. Six, John R. Haslett, Alexandra Maria Sänger, H.P. Gollmann |
| المصدر: | Europe PubMed Central |
| بيانات النشر: | Wiley, 2006. |
| سنة النشر: | 2006 |
| مصطلحات موضوعية: | medicine.medical_specialty, Myoblasts, Skeletal, Cyprinidae, Gene Expression, Dermomyotome, Biology, Muscle Development, biology.animal, Internal medicine, medicine, Animals, Myocyte, Cell Proliferation, MyoD Protein, Myosin Heavy Chains, Myogenesis, Cell growth, PAX7 Transcription Factor, Vertebrate, Embryo, Hyperplasia, medicine.disease, Cell biology, Endocrinology, Myogenic Regulatory Factors, PAX7, Developmental Biology |
| الوصف: | Present knowledge indicates that fibre recruitment (hyperplasia) in developing teleost fish occurs in three distinct phases. However, the origin and relationship of the myogenic precursors activated during the different phases remains unclear. Here, we address this issue using molecular techniques on embryos and larvae of pearlfish, a large cyprinid species. Results provide comprehensive molecular characterisation of cell recruitment over the three phases of myogenesis, identifying muscle types as they arise. Specifically, we show that the myogenic cells arising during 2nd phase myogenesis are clearly different from the myogenic cells arising during the 3rd phase and that the dermomyotome is a major source of myogenic cells driving 2nd phase hyperplasia. These findings are discussed in relation to their implications for the generality of vertebrate developmental patterns. |
| تدمد: | 1097-0177 1058-8388 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9be607ac8b286c268723fa5800892f https://doi.org/10.1002/dvdy.20950 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....3a9be607ac8b286c268723fa5800892f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10970177 10588388 |
|---|