Perplexed by PGx? Exploring the impact of pharmacogenomic results on medical management, disclosures and patient behavior
| العنوان: | Perplexed by PGx? Exploring the impact of pharmacogenomic results on medical management, disclosures and patient behavior |
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| المؤلفون: | Amy S Kaiser, Cheryl Shuman, Iris Cohn, David Chitayat, Allison Hazell, Larissa Waldman, Syed Wasim |
| المصدر: | Pharmacogenomics. 20:319-329 |
| بيانات النشر: | Future Medicine Ltd, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Adolescent, Genetic counseling, Pharmacist, Genetic Counseling, Disclosure, 030226 pharmacology & pharmacy, Cohort Studies, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Surveys and Questionnaires, Chart review, Genetics, medicine, Humans, Precision Medicine, Aged, Genetic testing, Pharmacology, medicine.diagnostic_test, business.industry, Middle Aged, Precision medicine, Patient Care Management, Pharmacogenomic Testing, Test (assessment), Patient Satisfaction, 030220 oncology & carcinogenesis, Family medicine, Pharmacogenomics, Molecular Medicine, Female, Perception, Patient behavior, Health Expenditures, Patient Participation, business |
| الوصف: | Pharmacogenomic (PGx) tests represent significant advances in precision medicine. Our aim was to explore perceptions following the return of PGx results, medication management, and disclosure to providers. We surveyed clients who had PGx testing and conducted a chart review of PGx results. Respectively, 84% and 94% of participants found pre- and post-test genetic counseling helpful. There was a significant difference in disclosure, while 6% disclosed results to a pharmacist, 50% disclosed to a physician. Qualitative analysis identified three themes: 1) psychological response; 2) perceived utility; 3) experiences with disclosure. Our study supports the provision of genetic counseling for a non-disease related genetic test. Benefits of PGx testing can be optimized by the collaboration of physicians, pharmacists, genetic counselors and patients. |
| تدمد: | 1744-8042 1462-2416 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac96cb75f58d965b7fa02f9000132a4 https://doi.org/10.2217/pgs-2018-0179 |
| رقم الأكسشن: | edsair.doi.dedup.....3ac96cb75f58d965b7fa02f9000132a4 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 17448042 14622416 |
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