التفاصيل البيبلوغرافية
العنوان:
N,N'-Diarylcyanoguanidines as antagonists of the CXCR2 and CXCR1 chemokine receptors
المؤلفون:
Henry M. Sarau , James J. Foley , Bryan Deborah L , Dulcie B. Schmidt , Miriam Burman , John D. Elliott , Hong Nie , Jakob Busch-Petersen , Widdowson Katherine L , Palovich Michael R , Wei Fu
المصدر:
Bioorganicmedicinal chemistry letters . 16(21)
سنة النشر:
2006
مصطلحات موضوعية:
Stereochemistry , Chemistry , Organic Chemistry , Clinical Biochemistry , Antagonist , Pharmaceutical Science , Biochemistry , Guanidines , In vitro , Receptors, Interleukin-8B , Receptors, Interleukin-8A , Chemokine receptor , Drug Discovery , Benzene derivatives , Molecular Medicine , Humans , CXC chemokine receptors , Selectivity , Molecular Biology
الوصف:
A series of N-(2-hydroxy-3-sulfonamidobenzene)-N'-arylcyanoguanidines was prepared. In general, these compounds proved to be potent antagonists of CXCR2 while the selectivity versus CXCR1 ranged from non-selective to >200-fold.
تدمد:
0960-894X
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b309d67f9a07917a495625385c7b8b8 https://pubmed.ncbi.nlm.nih.gov/16934456
حقوق:
CLOSED
رقم الأكسشن:
edsair.doi.dedup.....3b309d67f9a07917a495625385c7b8b8
قاعدة البيانات:
OpenAIRE
