Transient Compartmentalization of Simian Immunodeficiency Virus Variants in the Breast Milk of African Green Monkeys
| العنوان: | Transient Compartmentalization of Simian Immunodeficiency Virus Variants in the Breast Milk of African Green Monkeys |
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| المؤلفون: | Lisa Colvin, Thomas N. Denny, Joern E. Schmitz, C. Todd DeMarco, Shannon D. Smith, Sallie R. Permar, Christie Brinkley, Joshua D. Amos, Allen G. Rodrigo, Andrew B. Wilks, Steven H. Wu, Carrie Ho |
| المصدر: | Journal of Virology. 87:11292-11299 |
| بيانات النشر: | American Society for Microbiology, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | animal diseases, viruses, Immunology, Simian Acquired Immunodeficiency Syndrome, Biology, Breast milk, medicine.disease_cause, Microbiology, Cercopithecus aethiops, Virus, Plasma, fluids and secretions, Virology, Chlorocebus aethiops, medicine, Animals, Cluster Analysis, Phylogeny, Genetics, Milk, Human, Chlorocebus, virus diseases, food and beverages, Gene Products, env, Genetic Variation, Sequence Analysis, DNA, Compartmentalization (psychology), Simian immunodeficiency virus, biology.organism_classification, Viral replication, Insect Science, Pathogenesis and Immunity, Female, Simian Immunodeficiency Virus, African Green Monkey |
| الوصف: | Natural hosts of simian immunodeficiency virus (SIV), African green monkeys (AGMs), rarely transmit SIV via breast-feeding. In order to examine the genetic diversity of breast milk SIV variants in this limited-transmission setting, we performed phylogenetic analysis on envelope sequences of milk and plasma SIV variants of AGMs. Low-diversity milk virus populations were compartmentalized from that in plasma. However, this compartmentalization was transient, as the milk virus lineages did not persist longitudinally. |
| تدمد: | 1098-5514 0022-538X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1be28fe26238fe0a9da31b7457893d https://doi.org/10.1128/jvi.01643-13 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....3c1be28fe26238fe0a9da31b7457893d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10985514 0022538X |
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