Which Inner Ear Disorders Lie Behind a Selective Posterior Semicircular Canal Hypofunction on Video Head Impulse Test?
| العنوان: | Which Inner Ear Disorders Lie Behind a Selective Posterior Semicircular Canal Hypofunction on Video Head Impulse Test? |
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| المؤلفون: | Angelo Ghidini, Gian Gaetano Ferri, Cristina Brandolini, Andrea Castellucci, Valeria Del Vecchio, Gianluca Piras |
| المساهمون: | Castellucci, Andrea, Piras, Gianluca, Del Vecchio, Valeria, Ferri, Gian Gaetano, Ghidini, Angelo, Brandolini, Cristina, Castellucci, A., Piras, G., Del Vecchio, V., Ferri, G. G., Ghidini, A., Brandolini, C. |
| المصدر: | Otology & Neurotology. 42:573-584 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Benign paroxysmal positional vertigo, Semicircular Canal, Sudden sensorineural hearing lo, Inferior vestibular neuriti, Posterior semicircular canal, Lesion, 03 medical and health sciences, Vestibular schwannoma, 0302 clinical medicine, Retrospective Studie, Caloric Tests, medicine, Video head impulse test, Humans, Inner ear, 030223 otorhinolaryngology, Head Impulse Test, Meniere Disease, Retrospective Studies, Vestibular evoked myogenic potential, medicine.diagnostic_test, Posterior Semicircular Canal, business.industry, Benign paroxysmal positional vertigo , Inferior vestibular neuritis , Menière's disease , Posterior semicircular canal , Sudden sensorineural hearing loss , Vestibular evoked myogenic potentials , Vestibular schwannoma , Video head impulse test, Head impulse test, Middle Aged, Cerebellopontine angle, medicine.disease, Semicircular Canals, Sensory Systems, Pathophysiology, medicine.anatomical_structure, Otorhinolaryngology, Female, Neurology (clinical), Radiology, medicine.symptom, Audiometry, business, Menière's disease, 030217 neurology & neurosurgery, Caloric Test, Human |
| الوصف: | Objective: To assess all different patterns of associated abnormalities on audiometry, bithermal caloric test (BCT) and cervical/ocular vestibular-evoked myogenic potentials (VEMPs) to air/bone-conduction in patients with selective posterior semicircular canal (PSC) hypofunction and to correlate them with underlying disorders. Study Design: Retrospective review. Setting: Tertiary referral center. Patients: 51 patients (23 men, 28 women, mean age 57.5 yr) with isolated PSC deficit (one bilateral). Interventions: Correlation with instrumental data and underlying diagnoses. Main Outcome Measures: Video-oculographic findings, objective measurements on audiometry, BCT, VEMPs and video-head impulse test (vHIT). Results: Ongoing or previous acute vestibular loss (AVL) was diagnosed in 13 patients (25.5%, 3 inferior vestibular neuritis, 10 AVL with sudden sensorineural hearing loss [SSNHL]), Meniere's disease (MD) in 12 (23.5%), cerebellopontine angle (CPA) lesion in 9 (17.6%), various causes in 7 (13.7%), benign paroxysmal positional vertigo (BPPV) involving the non-ampullary arm of PSC in 5 cases (9.8%) whereas unknown pathology in 5 (9.8%). Involvement of at least one additional receptor besides PSC was seen in 89.8% of cases. Cochlear involvement was diagnosed in 74.5% with pure-tone average significantly greater in patients with AVL+SSNHL (p < 0.05). Overall involvement of labyrinthine receptors or afferents was highest in patients with AVL+SSNHL (p < 0.01), MD and CPA lesions (p < 0.05). Conclusions: Isolated loss of PSC function on vHIT is mostly accompanied by additional labyrinthine deficits that could only be identified through an accurate instrumental evaluation. Assessment of all receptors and afferents should be always pursued to identify the lesion site and better understand the underlying pathophysiological mechanisms. |
| وصف الملف: | STAMPA |
| تدمد: | 1537-4505 1531-7129 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2122df8310b16b16f78389cd1ac6e1 https://doi.org/10.1097/mao.0000000000002995 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....3c2122df8310b16b16f78389cd1ac6e1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15374505 15317129 |
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