Revisiting extracorporeal membrane oxygenation for ARDS in burns: A case series and review of the literature

التفاصيل البيبلوغرافية
العنوان: Revisiting extracorporeal membrane oxygenation for ARDS in burns: A case series and review of the literature
المؤلفون: Craig R. Ainsworth, Phillip E. Mason, Jeffrey DellaVolpe, Leopoldo C. Cancio, Kevin K. Chung
المصدر: Burns. 44:1433-1438
بيانات النشر: Elsevier BV, 2018.
سنة النشر: 2018
مصطلحات موضوعية: Adult, Male, Burn injury, ARDS, Body Surface Area, medicine.medical_treatment, Critical Care and Intensive Care Medicine, law.invention, Young Adult, 03 medical and health sciences, Extracorporeal Membrane Oxygenation, 0302 clinical medicine, law, Pneumonia, Bacterial, Extracorporeal membrane oxygenation, Humans, Medicine, Hospital Mortality, 030212 general & internal medicine, Retrospective Studies, Mechanical ventilation, Respiratory Distress Syndrome, business.industry, 030208 emergency & critical care medicine, Burn center, General Medicine, Middle Aged, Smoke Inhalation Injury, medicine.disease, Intensive care unit, surgical procedures, operative, Respiratory failure, Stevens-Johnson Syndrome, Anesthesia, Emergency Medicine, Female, Surgery, Burns, business, Total body surface area
الوصف: Introduction Recent reports on the use of extracorporeal membrane oxygenation (ECMO) in critically ill burn patients with Acute Respiratory Distress Syndrome (ARDS) recommended against the use of ECMO. The authors cited the high mortality rates associated with the use of ECMO in these patients with no appreciable benefit. Accumulating evidence from referral centers suggests improved survival in patients with ARDS receiving ECMO. We report our recent experience treating patients with severe ARDS with ECMO in a burn intensive care unit. Methods This is a case series of consecutive patients placed on ECMO at our burn center from the initiation of our program in September 2012 to September 2017. We included only adult patients who had been placed on ECMO with burn injury, TEN, or inhalation injury and severe ARDS. Results Fourteen patients with burn injury, inhalation injury or TEN were placed on ECMO from the initiation of the ECMO program to September 1st 2017. The average total body surface area burned in the 11 patients with burn injury was 27% (range 0.25–76%). The cause of ARDS in these patients included inhalation injury, airway trauma and bacterial pneumonia. Four patients had an inhalation injury and 1 patient had a grade 3 inhalation injury but no burn injury. In the majority of cases, prone positioning and use of neuromuscular blockade was also used in an attempt to improve oxygenation and patient synchrony with mechanical ventilation. The average time on ECMO was 276 h (range 63–539 h). Ten of the 14 patients survived to decanulation from ECMO (71%) and eight of 14 patients (57%) survived to hospital discharge. Conclusions To our knowledge, this is the lowest mortality rate reported to date in burn patients with ARDS place on ECMO. ECMO is a viable therapy that can be utilized successfully as a rescue modality when conventional interventions are unsuccessful.
تدمد: 0305-4179
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9cbcaec900ba90e107517911932916
https://doi.org/10.1016/j.burns.2018.05.008
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....3d9cbcaec900ba90e107517911932916
قاعدة البيانات: OpenAIRE