Lymphoscintigraphic Findings as Indicators of Lymphaticovenous Anastomosis Outcome in Patients With Extremity Lymphedema
| العنوان: | Lymphoscintigraphic Findings as Indicators of Lymphaticovenous Anastomosis Outcome in Patients With Extremity Lymphedema |
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| المؤلفون: | Byung Seok Moon, Seo Young Kang, Hai Jeon Yoon, Bom Sahn Kim, Hye Ok Kim, Kyong Je Woo |
| المصدر: | Clinical Nuclear Medicine. 46:549-555 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, 030218 nuclear medicine & medical imaging, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, Radiology, Nuclear Medicine and imaging, In patient, Lymphedema, Aged, Retrospective Studies, business.industry, Anastomosis, Surgical, Therapeutic effect, Retrospective cohort study, General Medicine, Middle Aged, medicine.disease, Trunk, Lymphaticovenous anastomosis, Treatment Outcome, Lymphatic system, Lower Extremity, 030220 oncology & carcinogenesis, Female, Lymph, Radiology, business, Lymphoscintigraphy |
| الوصف: | PURPOSE This study was performed to evaluate the usefulness of lymphoscintigraphy in predicting the surgical outcomes of lymphaticovenous anastomosis (LVA) in a patient with extremity lymphedema. PATIENTS AND METHODS We retrospectively evaluated 133 patients with extremity lymphedema who underwent lymphoscintigraphy followed by LVA surgery from February 2018 to March 2020. Lymphoscintigraphic findings were evaluated on the following parameters: the extent of dermal backflow (small/large), lymphatic flow patterns (trunk flow pattern/proximal-restricted pattern/distal-restricted pattern), visualization of lymph nodes, and collateral lymphatic vessels. The mean circumferential difference change before and after surgery, circumferential reduction (CR) rate (%), was used as the clinical outcome variables. RESULTS A decrease in circumference was observed in 93 (69.9%) of 133 patients after LVA. The extent of dermal backflow and lymphatic flow patterns was significantly correlated with improved clinical outcomes after LVA. The large extent of the dermal backflow group showed a more significant CR rate than the small extent (19.27% vs 1.24%, P = 0.005). The TP group showed the most significantly decreased CR rate to 21.46%, and the proximal-restricted pattern and distal-restricted pattern groups were -2.49% and -5.33%, respectively (P < 0.001). Multivariate analysis revealed that dermal backflow and lymphatic flow patterns were independent predictors of therapeutic outcome (P < 0.001). CONCLUSIONS Our study demonstrates that pretreatment lymphoscintigraphy may help predict the therapeutic effect of LVA in patients with extremity lymphedema. Furthermore, dermal backflow and lymphatic flow patterns are independent predictors of CR rate after LVA surgery for extremity lymphedema. |
| تدمد: | 1536-0229 0363-9762 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dde4af4058b002c323ab63ae31f5355 https://doi.org/10.1097/rlu.0000000000003630 |
| رقم الأكسشن: | edsair.doi.dedup.....3dde4af4058b002c323ab63ae31f5355 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15360229 03639762 |
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