Prognostic and clinicopathological value of miR-199b in cancers: a meta-analysis
| العنوان: | Prognostic and clinicopathological value of miR-199b in cancers: a meta-analysis |
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| المؤلفون: | Zhongxiang, Mao, Rongqiang, Liu, Min, Zhang, Wenbin, Liu, Dewei, Li, Hui, Li |
| المصدر: | Biomarkers in Medicine. 16:879-888 |
| بيانات النشر: | Future Medicine Ltd, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Gene Expression Regulation, Neoplastic, MicroRNAs, Lymphatic Metastasis, Biochemistry (medical), Clinical Biochemistry, Drug Discovery, Biomarkers, Tumor, Humans, Prognosis, Cell Proliferation |
| الوصف: | Background: The prognostic value of miR-199b in cancers has not been fully clarified. Methods: All articles evaluating the prognostic value of miR-199b in tumors were included. The hazard ratio (HR), odds ratio (OR) and 95% CI were calculated to assess the relationship between miR-199b expression and survival outcomes and clinicopathological features. Results: The combined results indicated that high miR-199b expression predicted favorable overall survival (OS) compared with low miR-199b expression (HR: 0.62, 95% CI: 0.44–0.87). In addition, high miR-199b expression had a significant correlation with the prevention of lymph node metastasis (OR: 0.39, 95% CI: 0.25–0.59). Conclusion: MiR-199b can be used as an effective prognostic marker in cancers. |
| تدمد: | 1752-0371 1752-0363 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f77c0ac1b98e81cc67d9674fbd1a9a7 https://doi.org/10.2217/bmm-2022-0138 |
| رقم الأكسشن: | edsair.doi.dedup.....3f77c0ac1b98e81cc67d9674fbd1a9a7 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 17520371 17520363 |
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