Treatment outcomes according to the macroscopic tumor type in locally advanced esophageal squamous cell carcinoma treated by chemoradiotherapy
| العنوان: | Treatment outcomes according to the macroscopic tumor type in locally advanced esophageal squamous cell carcinoma treated by chemoradiotherapy |
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| المؤلفون: | Katsunori Shinozaki, Katsumaro Kubo, Koichi Wadasaki |
| المصدر: | Japanese Journal of Radiology. 37:341-349 |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Esophageal Neoplasms, medicine.medical_treatment, Treatment outcome, Locally advanced, Esophageal squamous cell carcinoma, Gastroenterology, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, Tumor type, Aged, Aged, 80 and over, medicine.diagnostic_test, business.industry, Endoscopy, Chemoradiotherapy, Middle Aged, Esophageal cancer, medicine.disease, Survival Analysis, Radiation therapy, Treatment Outcome, 030220 oncology & carcinogenesis, Female, Esophageal Squamous Cell Carcinoma, business, Follow-Up Studies |
| الوصف: | To identify predictive factors for local control of locally advanced esophageal cancer by chemoradiotherapy, the relationship between clinical features, including macroscopic tumor type, and treatment outcome was analyzed in 83 patients. Macroscopic tumor type was defined by endoscopy as follows: type 1: protruding type; type 2: ulcerative and localized type; type 3: ulcerative and infiltrative type; type 4: diffusely infiltrative type; and type 5: unclassifiable type. We analyzed the overall survival, cause-specific survival, local progression-free rate, and predictive factors for locally advanced esophageal cancer after chemoradiotherapy. The median follow-up period at the time of evaluation was 59 months among survivors. The 5-year overall survival, cause-specific survival, and local progression-free rates for type 1 and other types were 37.0% and 23.3% (P = 0.4255), 71.8% and 30.3% (P = 0.0325), and 100% and 63.3% (P = 0.0246), respectively. Macroscopic tumor type (type 1) was the most significant predictive factor of cause-specific survival and local progression-free rates. Macroscopic tumor type 1 was the significant favorable predictive factor for local control. The study results suggested that the macroscopic tumor type was useful in predicting tumor responses. |
| تدمد: | 1867-108X 1867-1071 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401977d87875c8469114879b8de640e0 https://doi.org/10.1007/s11604-019-00814-6 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....401977d87875c8469114879b8de640e0 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 1867108X 18671071 |
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