التفاصيل البيبلوغرافية
العنوان:
Synthesis of (+)-solenopsin via Pd-catalyzed N-alkylation and cyclization
المؤلفون:
Hidefumi Makabe , Atsushi Kawamura , Kana Suzuki , Yasunao Hattori
المصدر:
Bioscience, Biotechnology, and Biochemistry . 85:223-227
بيانات النشر:
Informa UK Limited, 2021.
سنة النشر:
2021
مصطلحات موضوعية:
Models, Molecular , Alkylation , Double bond , Molecular Conformation , Chemistry Techniques, Synthetic , 010402 general chemistry , Ring (chemistry) , 01 natural sciences , Applied Microbiology and Biotechnology , Biochemistry , Medicinal chemistry , Catalysis , Analytical Chemistry , chemistry.chemical_compound , Alkaloids , Solenopsin , Moiety , Molecular Biology , chemistry.chemical_classification , 010405 organic chemistry , Organic Chemistry , Stereoisomerism , General Medicine , 0104 chemical sciences , chemistry , Cyclization , Stereoselectivity , Piperidine , Palladium , Biotechnology
الوصف:
Synthesis of (+)-solenopsin, a 2,6-disubstituted piperidine alkaloid, isolated from fire ants (Solenopsis), was achieved. Stereoselective construction of trans-2,6-piperidine ring moiety was performed using palladium-catalyzed cyclization. Chain elongation using Grubbs 2nd catalyst followed by the reduction of double bond and the deprotection of the Cbz group afforded (+)-solenopsin.
تدمد:
1347-6947
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404f47984227c622f22d089d5df71987 https://doi.org/10.1093/bbb/zbaa014
حقوق:
OPEN
رقم الأكسشن:
edsair.doi.dedup.....404f47984227c622f22d089d5df71987
قاعدة البيانات:
OpenAIRE
