The comparison of feasibility and safety on fiberoptic guided intubation under conscious sedation with remifentanil and propofol
| العنوان: | The comparison of feasibility and safety on fiberoptic guided intubation under conscious sedation with remifentanil and propofol |
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| المؤلفون: | Daelim Jee, Jun Sakong, Hae Mi Lee |
| المصدر: | Korean Journal of Anesthesiology, Vol 65, Iss 3, Pp 215-220 (2013) Korean Journal of Anesthesiology |
| بيانات النشر: | Korean Society of Anesthesiologists, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Clinical Research Article, propofol, business.industry, medicine.medical_treatment, Sedation, Remifentanil, Target controlled infusion, lcsh:RD78.3-87.3, Anesthesiology and Pain Medicine, Pharyngeal reflex, lcsh:Anesthesiology, Anesthesia, gag reflex, Medicine, Intubation, medicine.symptom, business, Propofol, Airway, Fiberoptic intubation, medicine.drug, remifentanil |
| الوصف: | Background: Oropharyngeal manipulation is problematic when patients have a gag reflex. Sedation can suppress gag reflex, but can cause serious airway problems. We compared remifentanil (Group R) and propofol (Group P) in terms of cooperation and loss of gag reflex, while drugs were administered incrementally using target controlled infusion (TCI). Methods: Fifty seven patients who required awake fiberoptic intubation were randomized to Group R or Group P. After measurement of baseline gag trigger point index (GTPI), TCI was set to effect-site concentration (Ce) of 1 ng/ml (Group R) or 1 μg/ml (Group P), then titrated by 0.5 increment until GTPI score reached 0. The incidence of drop-out and decreased cooperation, Ramsay sedation scale (RSS) and Ce at loss of GR, and complications were assessed. Results: Seven patients were dropped out in Group P due to deep sedation and disobedient behavior, but none in Group R (P = 0.015). Gag reflex suppressed as RSS increased in both groups (P < 0.001), however, the incidence of elimination of gag reflex clustered at RSS 2 in Group R (P < 0.001), whereas it was evenly distributed in Group P (P = 0.20). The incidence of patients who were spontaneously roused (gag reflex elimination at RSS 1 and 2) were higher in Group R than in Group P (P = 0.002). Conclusions: Deep sedation and impaired cooperation were observed only in Group P and spontaneously roused patients were higher in Group R, suggesting that remifentanil is more suitable for cooperative elimination of GR. (Korean J Anesthesiol 2013; 65: 215-220) |
| اللغة: | English |
| تدمد: | 2005-7563 2005-6419 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408a854dcb03110d6f402db018ef8422 http://ekja.org/upload/pdf/kjae-65-215.pdf |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....408a854dcb03110d6f402db018ef8422 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20057563 20056419 |
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