Clinicopathological characteristics and prognosis of resected cases of carcinoid tumors of the lung

التفاصيل البيبلوغرافية
العنوان: Clinicopathological characteristics and prognosis of resected cases of carcinoid tumors of the lung
المؤلفون: Zhi Yang, Yong Duan, Shaofa Xu, Zitong Wang
المصدر: Thoracic Cancer
بيانات النشر: Wiley, 2016.
سنة النشر: 2016
مصطلحات موضوعية: Adult, Male, Pulmonary and Respiratory Medicine, Pathology, medicine.medical_specialty, Lung Neoplasms, Adolescent, Carcinoid tumors, Patient characteristics, Carcinoid Tumor, Gastroenterology, surgery, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, In patient, Child, Lung cancer, Aged, Retrospective Studies, Univariate analysis, Lung, Tumor size, business.industry, Radical Lymph Node Dissection, Original Articles, General Medicine, Middle Aged, Prognosis, medicine.disease, Carcinoid, Survival Rate, lung cancer, medicine.anatomical_structure, 030228 respiratory system, Oncology, 030220 oncology & carcinogenesis, Lymph Node Excision, Original Article, Female, business
الوصف: Background Lung carcinoid tumors are rare, low-grade, malignant neoplasms with some unclear features. The aim of this study was to analyze clinicopathological features and long-term survival in patients with primary lung carcinoid tumors. Methods Patients who underwent surgery in our clinic and were diagnosed with carcinoid tumors, between August 1997 and July 2012, were included in the study. Patient characteristics and clinicopathological factors were retrospectively evaluated. Results Bronchial carcinoids comprised only 1.0% of lung cancer cases treated by resection. They are classified into two distinct categories: typical carcinoid (TC) and atypical carcinoid (AC) tumors. AC tumors occurred more frequently in younger patients and in smokers, and had a poorer prognosis than TC tumors. Overall three and five-year survival rates for TC and AC were 92.6% and 81.1%, respectively. Univariate analysis showed that tumor size ( P = 0.012) and histological type ( P = 0.013) are prognostic factors. Multivariate analysis revealed that only tumor size ( P = 0.044) was an independent prognostic factor. Conclusions The prognosis for bronchial carcinoid tumors was better than other types of lung cancer and TC was significantly better than AC. Radical lymph node dissection was the best treatment, with complete removal of the tumor. Tumor size was an independent prognostic factor for bronchial carcinoid tumors.
تدمد: 1759-7714
1759-7706
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4104e16e8f07244e82ef604fe0ac8e3c
https://doi.org/10.1111/1759-7714.12377
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....4104e16e8f07244e82ef604fe0ac8e3c
قاعدة البيانات: OpenAIRE