Introducing malaria rapid diagnostic tests in private medicine retail outlets: A systematic literature review
| العنوان: | Introducing malaria rapid diagnostic tests in private medicine retail outlets: A systematic literature review |
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| المؤلفون: | Andrea Cutherell, Obinna Onwujekwe, Abigail Ward, Christopher J. M. Whitty, Evelyn K. Ansah, Sham Lal, Ian Boulton, Elizabeth Streat, Catherine Goodman, Nora Petty, Günther Fink, David Schellenberg, Katia Bruxvoort, Siân E. Clarke, Katie Eves, Shunmay Yeung, Caitlin Dolkart, Anthony K. Mbonye, Julie Pontarollo, Eleanor Hutchinson, Toby Leslie, Stephen Poyer, Theodoor Visser, Lawrence M. Barat, Clare I R Chandler, Jennifer Anyanti, Virginia Wiseman, Justin M. Cohen, Jessica Cohen, Kathleen Maloney, Richard Allan, Jane Cunningham |
| المصدر: | PLoS ONE, Vol 12, Iss 3, p e0173093 (2017) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Economics, Social Sciences, lcsh:Medicine, 0302 clinical medicine, Antibiotics, Health care, Medicine and Health Sciences, 030212 general & internal medicine, lcsh:Science, health care economics and organizations, Multidisciplinary, Pharmaceutics, Antimicrobials, Public sector, Drug Information, 1. No poverty, Commerce, Drugs, 3. Good health, Systematic review, Private Sector, Research Article, medicine.medical_specialty, Referral, Patients, 030231 tropical medicine, MEDLINE, Pharmacy, Microbiology, 03 medical and health sciences, Antimalarials, Drug Therapy, Microbial Control, parasitic diseases, medicine, Parasitic Diseases, Humans, Pharmacology, Drug Screening, Vendors, business.industry, lcsh:R, Biology and Life Sciences, Private sector, medicine.disease, Tropical Diseases, Malaria, Health Care, Family medicine, lcsh:Q, Reagent Kits, Diagnostic, business |
| الوصف: | BACKGROUND: Many patients with malaria-like symptoms seek treatment in private medicine retail outlets (PMR) that distribute malaria medicines but do not traditionally provide diagnostic services, potentially leading to overtreatment with antimalarial drugs. To achieve universal access to prompt parasite-based diagnosis, many malaria-endemic countries are considering scaling up malaria rapid diagnostic tests (RDTs) in these outlets, an intervention that may require legislative changes and major investments in supporting programs and infrastructures. This review identifies studies that introduced malaria RDTs in PMRs and examines study outcomes and success factors to inform scale up decisions. METHODS: Published and unpublished studies that introduced malaria RDTs in PMRs were systematically identified and reviewed. Literature published before November 2016 was searched in six electronic databases, and unpublished studies were identified through personal contacts and stakeholder meetings. Outcomes were extracted from publications or provided by principal investigators. RESULTS: Six published and six unpublished studies were found. Most studies took place in sub-Saharan Africa and were small-scale pilots of RDT introduction in drug shops or pharmacies. None of the studies assessed large-scale implementation in PMRs. RDT uptake varied widely from 8%-100%. Provision of artemisinin-based combination therapy (ACT) for patients testing positive ranged from 30%-99%, and was more than 85% in five studies. Of those testing negative, provision of antimalarials varied from 2%-83% and was less than 20% in eight studies. Longer provider training, lower RDT retail prices and frequent supervision appeared to have a positive effect on RDT uptake and provider adherence to test results. Performance of RDTs by PMR vendors was generally good, but disposal of medical waste and referral of patients to public facilities were common challenges. CONCLUSIONS: Expanding services of PMRs to include malaria diagnostic services may hold great promise to improve malaria case management and curb overtreatment with antimalarials. However, doing so will require careful planning, investment and additional research to develop and sustain effective training, supervision, waste-management, referral and surveillance programs beyond the public sector. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4156b699f9f6e2a004276b5e567cc4ef http://europepmc.org/articles/PMC5333947?pdf=render |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....4156b699f9f6e2a004276b5e567cc4ef |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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