Artifact rates for 2D retinal nerve fiber layer thickness versus 3d neuroretinal rim thickness using spectral-domain optical coherence tomography
| العنوان: | Artifact rates for 2D retinal nerve fiber layer thickness versus 3d neuroretinal rim thickness using spectral-domain optical coherence tomography |
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| المؤلفون: | Eric Shieh, Brett E. Bouma, Teresa C. Chen, Benjamin J. Vakoc, Edem Tsikata, Elli A. Park, Boy Braaf, Johannes F. de Boer, Jenny Jyoung Lee |
| المساهمون: | Ophthalmology, Amsterdam Neuroscience - Brain Imaging, Biophotonics and Medical Imaging, LaserLaB - Biophotonics and Microscopy |
| المصدر: | Translational Vision Science and Technology, 9(10):10, 1-12. Association for Research in Vision and Ophthalmology Inc. Park, E A, Tsikata, E, Lee, J J, Shieh, E, Braaf, B, Vakoc, B J, Bouma, B E, de Boer, J F & Chen, T C 2020, ' Artifact rates for 2D retinal nerve fiber layer thickness versus 3d neuroretinal rim thickness using spectral-domain optical coherence tomography ', Translational Vision Science and Technology, vol. 9, no. 10, 10, pp. 1-12 . https://doi.org/10.1167/tvst.9.10.10 Translational Vision Science & Technology Translational Vision Science and Technology, 9(10):10, 1-12. Association for Research in Vision and Ophthalmology |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, genetic structures, Optic nerve, Optic Disk, Biomedical Engineering, Nerve fiber layer, Glaucoma, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Nerve Fibers, Optical coherence tomography, Ophthalmology, medicine, Humans, Artifact (error), medicine.diagnostic_test, business.industry, Retinal, medicine.disease, Minimum distance band, Confidence interval, eye diseases, 030104 developmental biology, medicine.anatomical_structure, chemistry, Neuroretinal rim, Artifact, 030221 ophthalmology & optometry, sense organs, business, Artifacts, Tomography, Optical Coherence |
| الوصف: | Purpose: To compare the rates of clinically significant artifacts for two-dimensional peripapillary retinal nerve fiber layer (RNFL) thickness versus three-dimensional (3D) neuroretinal rim thickness using spectral-domain optical coherence tomography (SD-OCT). Methods: Only one eye per patient was used for analysis of 120 glaucoma patients and 114 normal patients. For RNFL scans and optic nerve scans, 15 artifact types were calculated per B-scan and per eye. Neuroretinal rim tissue was quantified by the minimum distance band (MDB). Global MDB neuroretinal rim thicknesses were calculated before and after manual deletion of B-scans with artifacts and subsequent automated interpo-lation. A clinically significant artifact was defined as one requiring manual correction or repeat scanning. Results: Among glaucomatous eyes, artifact rates per B-scan were significantly more common in RNFL scans (61.7%, 74 of 120) compared to B-scans in neuroretinal rim volume scans (20.9%, 1423 of 6820) (95% confidence interval [CI], 31.6–50.0; P < 0.0001). For clinically significant artifact rates per eye, optic nerve scans had significantly fewer artifacts (15.8% of glaucomatous eyes, 13.2% of normal eyes) compared to RNFL scans (61.7% of glaucomatous eyes, 25.4% of normal eyes) (glaucoma group: 95% CI, 34.1–57.5, P < 0.0001; normal group: 95% CI, 1.3–23.3, P = 0.03). Conclusions: Compared to the most commonly used RNFL thickness scans, optic nerve volume scans less frequently require manual correction or repeat scanning to obtain accurate measurements. Translational Relevance: This paper illustrates the potential for 3D OCT algorithms to improve in vivo imaging in glaucoma. |
| اللغة: | English |
| تدمد: | 2164-2591 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418bac3dd9071c029abc2c6cde5dc9de http://www.scopus.com/inward/record.url?scp=85090629821&partnerID=8YFLogxK |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....418bac3dd9071c029abc2c6cde5dc9de |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 21642591 |
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