The COVID-19 pandemic situation that overwhelmed us still strongly questions university teaching today. The research reports a classroom’s activity based on self-assessment (SA) and peer-feedback (PF)activities. The result is connected to the combination of three key points for effective teaching: 1) an active role of the students involved in the activity, 2) an effective use of technology based on a Student Response System (SRS), and 3) a sustained pedagogical training for teachers suddenly catapulted to new teaching methods. The design used, developed in the Italian university context, can be developed totally online, guaranteeing new skills and new learning, in view of a hypothetical, and not so unexpected, return to distance learning.