التفاصيل البيبلوغرافية
العنوان:
Discovery and SAR of novel tetrahydropyrrolo[3,4-c]pyrazoles as inhibitors of the N-type calcium channel
المؤلفون:
Ning Qin , Mary Lou Lubin , Michael R. Brandt , Edward J. Beck , Zhihua Sui , Christopher M. Flores , Michael P. Winters , Yi Liu , Michael P. Neeper , Michael F.A. Finley , Wall Mark , Nalin L. Subasinghe
المصدر:
Bioorganicmedicinal chemistry letters . 24(9)
سنة النشر:
2014
مصطلحات موضوعية:
Chemistry , Stereochemistry , Calcium channel , Organic Chemistry , Clinical Biochemistry , Pharmaceutical Science , N-type calcium channel , Calcium Channel Blockers , Biochemistry , Rats , Structure-Activity Relationship , Calcium Channels, N-Type , Drug Discovery , Microsomes, Liver , Molecular Medicine , Animals , Humans , Pyrazoles , Chronic Pain , Molecular Biology
الوصف:
A novel series of substituted tetrahydropyrrolo[3,4-c]pyrazoles were investigated as blockers of the N-type calcium channel (Cav2.2 channels), a chronic pain target.
تدمد:
1464-3405
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ec7ef54f1ffc10974d794a05d211f0 https://pubmed.ncbi.nlm.nih.gov/24726802
حقوق:
CLOSED
رقم الأكسشن:
edsair.doi.dedup.....42ec7ef54f1ffc10974d794a05d211f0
قاعدة البيانات:
OpenAIRE
