[Badia JM, Batlle M, Juvany M, Ruiz-de León P] Department of Surgery, Hospital General Granollers, Universitat Internacional de Catalunya, Granollers, Spain. [Sagalés M] Department of Clinical Pharmacy, Hospital General Granollers, Granollers, Spain. [Pulido MA] Department of Clinical Microbiology, Hospital General Granollers, Granollers, Spain. [Molist G] Department of Statistics and Research, Hospital General Granollers, Granollers, Spain. [Cuquet J] Infectious Diseases Unit, Hospital General Granollers, Granollers, Spain, Hospital General de Granollers
المصدر:
Antibiotics, Vol 10, Iss 11, p 11 (2021) Scientia Antibiotics Volume 10 Issue 1
Antibiotic stewardship programs optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes. In this prospective interventional study, a multidisciplinary team led by surgeons implemented a program aimed at shortening the duration of antibiotic treatment < 7 days. The impact of the intervention on antibiotic consumption adjusted to bed-days and discharges, and the isolation of multiresistant bacteria (MRB) was also studied. Furthermore, the surgeons were surveyed regarding their beliefs and feelings about the program. Out of 1409 patients, 40.7% received antibiotic therapy. Treatment continued for over 7 days in 21.5% of cases, and, as can be expected, source control was achieved in only 48.8% of these cases. The recommendations were followed in 90.2% of cases, the most frequent being to withdraw the treatment (55.6%). During the first 16 months of the intervention, a sharp decrease in the percentage of extended treatments, with R2 = 0.111 was observed. The program was very well accepted by surgeons, and achieved a decrease in both the consumption of carbapenems and in the number of MRB isolations. Multidisciplinary stewardship teams led by surgeons seem to be well received and able to better manage antibiotic prescription in surgery.
