Tooth Regeneration: Insights from Tooth Development and Spatial-Temporal Control of Bioactive Drug Release
| العنوان: | Tooth Regeneration: Insights from Tooth Development and Spatial-Temporal Control of Bioactive Drug Release |
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| المؤلفون: | Baicheng Bao, Jianhan Ren, Delan Huang, Chen Zhou, Zhicai Feng, Chenyu Guan, Runze Li, Weicai Wang |
| المصدر: | Stem Cell Reviews and Reports |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0301 basic medicine, Dentistry, Spatial-temporal control of drug release, Context (language use), Biodegradable Plastics, 02 engineering and technology, Tooth development, Article, Tooth Loss, 03 medical and health sciences, stomatognathic system, Tooth loss, Humans, Regeneration, Medicine, Control release, Tooth regeneration, Tissue Engineering, business.industry, 021001 nanoscience & nanotechnology, Drug Liberation, stomatognathic diseases, 030104 developmental biology, Biodegradable materials, Drug release, Cytokines, medicine.symptom, 0210 nano-technology, business, Tooth |
| الوصف: | Tooth defect and tooth loss are common clinical diseases in stomatology. Compared with the traditional oral restoration treatment, tooth regeneration has unique advantages and is currently the focus of oral biomedical research. It is known that dozens of cytokines/growth factors and other bioactive factors are expressed in a spatial-temporal pattern during tooth development. On the other hand, the technology for spatial-temporal control of drug release has been intensively studied and well developed recently, making control release of these bioactive factors mimicking spatial-temporal pattern more feasible than ever for the purpose of tooth regeneration. This article reviews the research progress on the tooth development and discusses the future of tooth regeneration in the context of spatial-temporal release of developmental factors. |
| تدمد: | 2629-3277 2629-3269 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446f2a5ee0bd6d0ce5b8554cd3073cae https://doi.org/10.1007/s12015-019-09940-0 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....446f2a5ee0bd6d0ce5b8554cd3073cae |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 26293277 26293269 |
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