Guillain-Barré syndrome as the first presentation of human immunodeficiency virus infection

التفاصيل البيبلوغرافية
العنوان: Guillain-Barré syndrome as the first presentation of human immunodeficiency virus infection
المؤلفون: Gonçalo Cruz, José Saraiva da Cunha, Patrícia Marques, Helena Alves, J.E. Serra, Bruno Silva, Mariana Carneiro Lopes, Eugénia Ferreira
المصدر: BMC Neurology, Vol 21, Iss 1, Pp 1-4 (2021)
BMC Neurology
بيانات النشر: Springer Science and Business Media LLC, 2021.
سنة النشر: 2021
مصطلحات موضوعية: Male, medicine.medical_specialty, Weakness, Pediatrics, Neurology, Antiretroviral Therapy, Case Report, HIV Infections, Primary Dysautonomias, Disease, Guillain-Barre Syndrome, Adrenal Cortex Hormones, Antiretroviral Therapy, Highly Active, medicine, Humans, RC346-429, Muscle Weakness, Guillain-Barre syndrome, business.industry, Medical record, Immunoglobulins, Intravenous, HIV, General Medicine, Middle Aged, medicine.disease, Regimen, Treatment Outcome, Neurology. Diseases of the nervous system, Neurology (clinical), Neurosurgery, medicine.symptom, business, Complication
الوصف: Aim Antiretroviral therapy (ART) development has reduced the severity of neurological complications of the human immunodeficiency virus (HIV), but they remain prevalent and need prompt recognition. Acute inflammatory demyelinating polyneuropathy (AIDP) is a rare complication of human immunodeficiency virus (HIV) infection that may appear at any stage of the disease. In this case, AIDP represents a late presentation of HIV infection. Methods Descriptive study. Patient data were collected from their medical records and by health assessment interviews. Results We report a case of a 52-year-old male with acute lower limb weakness. Given the suggestive clinical presentation of AIDP and a positive HIV test, intravenous immunoglobulin (IVIG) was administered along with antiretroviral therapy. Progressive weakness to the upper limbs, autonomic dysfunction, and pain was observed. The second regimen of IVIG plus corticosteroids was administered. Muscle strength improved after three weeks. Conclusions Screening for HIV in a patient with AIDP may provide a better outcome because of the early start of ART with good central nervous system penetration in HIV-infected patients.
تدمد: 1471-2377
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e21acfaafa67a2943fe6ff001b6ba5
https://doi.org/10.1186/s12883-021-02350-1
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....44e21acfaafa67a2943fe6ff001b6ba5
قاعدة البيانات: OpenAIRE