High preoperative plasma fibrinogen is an independent predictor of distant metastasis and poor prognosis in renal cell carcinoma
| العنوان: | High preoperative plasma fibrinogen is an independent predictor of distant metastasis and poor prognosis in renal cell carcinoma |
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| المؤلفون: | Lei Zhou, Yan Hui Zhang, Xin Yao, Jian hua Zheng, Qing Yang, Jun Du, Xu Sheng Chen |
| المصدر: | International Journal of Clinical Oncology. 18:517-523 |
| بيانات النشر: | Springer Science and Business Media LLC, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adult, Male, Oncology, medicine.medical_specialty, medicine.medical_treatment, Fibrinogen, Gastroenterology, Disease-Free Survival, Plasma, chemistry.chemical_compound, Renal cell carcinoma, Surgical oncology, Internal medicine, Lactate dehydrogenase, medicine, Carcinoma, Humans, Neoplasm Metastasis, Carcinoma, Renal Cell, Aged, Retrospective Studies, Univariate analysis, business.industry, Hematology, General Medicine, Middle Aged, Prognosis, medicine.disease, Kidney Neoplasms, Nephrectomy, chemistry, Preoperative Period, T-stage, Female, Surgery, business, medicine.drug |
| الوصف: | We aimed to evaluate the association of preoperative plasma fibrinogen levels with the clinicopathological parameters, disease-free survival, and overall survival in patients with renal cell carcinoma. We retrospectively studied 286 patients with renal cell carcinoma who underwent radical nephrectomy from 2000 to 2003 at one center. The plasma fibrinogen was routinely determined before operation in all patients. The correlation of preoperative plasma fibrinogen levels with clinicopathological findings was evaluated by t-test or analysis of variance (ANOVA) methods. As well, univariate and multivariate analyses were used to determine the association between the preoperative level of plasma fibrinogen and survival duration. An elevated level of plasma fibrinogen was positively related to the Fuhrman grade (P |
| تدمد: | 1437-7772 1341-9625 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e54e68e4b2037b677e9cf7d350c125 https://doi.org/10.1007/s10147-012-0412-x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....44e54e68e4b2037b677e9cf7d350c125 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14377772 13419625 |
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