Neurofeedback of Slow Cortical Potentials in Children with Attention-Deficit/Hyperactivity Disorder: A Multicenter Randomized Trial Controlling for Unspecific Effects
| العنوان: | Neurofeedback of Slow Cortical Potentials in Children with Attention-Deficit/Hyperactivity Disorder: A Multicenter Randomized Trial Controlling for Unspecific Effects |
|---|---|
| المؤلفون: | Strehl, Ute, Aggensteiner, Pascal, Wachtlin, Daniel, Brandeis, Daniel, Albrecht, Björn, Arana, Maria, Bach, Christiane, Banaschewski, Tobias, Bogen, Thorsten, Flaig-Röhr, Andrea, Freitag, Christine M., Fuchsenberger, Yvonne, Gest, Stephanie, Gevensleben, Holger, Herde, Laura, Hohmann, Sarah, Legenbauer, Tanja, Marx, Anna-Maria, Millenet, Sabina, Pniewski, Benjamin, Rothenberger, Aribert, Ruckes, Christian, Wörz, Sonja, Holtmann, Martin |
| المساهمون: | University of Zurich, Strehl, Ute |
| المصدر: | Frontiers in Human Neuroscience, 11 Frontiers in Human Neuroscience |
| بيانات النشر: | Frontiers Media, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | specificity, 610 Medicine & health, neurofeedback, randomized controlled study, 10058 Department of Child and Adolescent Psychiatry, EMG feedback, slow cortical potentials, 3206 Neuropsychology and Physiological Psychology, Behavioral Neuroscience, Psychiatry and Mental health, 2738 Psychiatry and Mental Health, Neuropsychology and Physiological Psychology, Neurology, 10076 Center for Integrative Human Physiology, 2808 Neurology, 2802 Behavioral Neuroscience, ADHD, 10064 Neuroscience Center Zurich, 2803 Biological Psychiatry, Biological Psychiatry, Neuroscience, Original Research |
| الوصف: | Background: Neurofeedback (NF) in children with attention-deficit/hyperactivity disorder (ADHD) has been investigated in a series of studies over the last years. Previous studies did not unanimously support NF as a treatment in ADHD. Most studies did not control for unspecific treatment effects and did not demonstrate that self-regulation took place. The present study examined the efficacy of NF in comparison to electromyographic (EMG) feedback to control for unspecific effects of the treatment, and assessed self-regulation of slow cortical potentials (SCPs). Methods: A total of 150 children aged 7–9 years diagnosed with ADHD (82% male; 43% medicated) were randomized to 25 sessions of feedback of SCPs (NF) or feedback of coordination of the supraspinatus muscles (EMG). The primary endpoint was the change in parents’ ratings of ADHD core symptoms 4 weeks after the end of treatment compared to pre-tests. Results: Children in both groups showed reduced ADHD-core symptoms (NF 0.3, 95% CI -0.42 to -0.18; EMG 0.13, 95% CI -0.26 to -0.01). NF showed a significant superiority over EMG (treatment difference 0.17, 95% CI 0.02–0.3, p = 0.02). This yielded an effect size (ES) of d = 0.57 without and 0.40 with baseline observation carried forward (BOCF). The sensitivity analysis confirmed the primary result. Successful self-regulation of brain activity was observed only in NF. As a secondary result teachers reported no superior improvement from NF compared to EMG, but within-group analysis revealed effects of NF on the global ADHD score, inattention, and impulsivity. In contrast, EMG feedback did not result in changes despite more pronounced self-regulation learning. Conclusions: Based on the primary parent-rated outcome NF proved to be superior to a semi-active EMG feedback treatment. The study supports the feasibility and efficacy of NF in a large sample of children with ADHD, based on both specific and unspecific effects. Frontiers in Human Neuroscience, 11 ISSN:1662-5161 |
| وصف الملف: | application/application/pdf; ZORA136740.pdf - application/pdf |
| اللغة: | English |
| تدمد: | 1662-5161 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451501ce89861a280528cc3e60a38dba https://hdl.handle.net/20.500.11850/191792 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....451501ce89861a280528cc3e60a38dba |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16625161 |
|---|