Supplementary Methods from A New Triglycyl Peptide Linker for Antibody–Drug Conjugates (ADCs) with Improved Targeted Killing of Cancer Cells

التفاصيل البيبلوغرافية
العنوان: Supplementary Methods from A New Triglycyl Peptide Linker for Antibody–Drug Conjugates (ADCs) with Improved Targeted Killing of Cancer Cells
المؤلفون: Wayne C. Widdison, Ravi V.J. Chari, John M. Lambert, Hans K. Erickson, Qifeng Qiu, Rui Wu, Paulin Salomon, Rabih Gabriel, Anna Skaletskaya, Juliet A. Costoplus, Karen Veale, Leanne Lanieri, Jennifer A. Coccia, Gregory E. Jones, Ling Dong, Nathan Fishkin, E. Erica Hong, Katharine C. Lai, Yelena V. Kovtun, Jose Ponte, Yulius Y. Setiady, Rajeeva Singh
بيانات النشر: American Association for Cancer Research (AACR), 2023.
سنة النشر: 2023
الوصف: Supplementary Methods (S1-S3). Supplementary Method S1: Synthesis of di-, tri-, tetra-glycyl, and valine-citrulline-glycine peptide linkers and catabolites. Supplementary Method S2: Test of in vitro cytotoxicity, cell-cycle inhibition, and bystander cytotoxic activity of ADCs. Supplementary Method S3: Catabolism of [3H]-labeled and non-radiolabeled CX and SMCC ADCs by cancer cells.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b6d4b4f9c44ca6353724746b9d8c98
https://doi.org/10.1158/1535-7163.22503028.v1
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....45b6d4b4f9c44ca6353724746b9d8c98
قاعدة البيانات: OpenAIRE