LncRNA EIF3J-AS1 enhanced esophageal cancer invasion via regulating AKT1 expression through sponging miR-373-3p
| العنوان: | LncRNA EIF3J-AS1 enhanced esophageal cancer invasion via regulating AKT1 expression through sponging miR-373-3p |
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| المؤلفون: | Qing Li, Jinxiao Liang, Wei-Tian Wei, Liang Wang, Jian Zeng, Jiang-Feng Wang |
| المصدر: | Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020) Scientific Reports |
| بيانات النشر: | Nature Portfolio, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, Male, Esophageal Neoplasms, Carcinogenesis, Cell, AKT1, Gene Expression, Apoptosis, medicine.disease_cause, Metastasis, 0302 clinical medicine, Cell Movement, Medicine, Cancer, Aged, 80 and over, Gene knockdown, Multidisciplinary, Esophageal cancer, Middle Aged, medicine.anatomical_structure, Lymphatic Metastasis, Disease Progression, Female, RNA, Long Noncoding, Adult, Cell biology, Science, Microbiology, Article, 03 medical and health sciences, In vivo, Cell Line, Tumor, Genetics, Humans, Neoplasm Invasiveness, Aged, Cell Proliferation, business.industry, Competing endogenous RNA, medicine.disease, MicroRNAs, 030104 developmental biology, Cancer research, business, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery |
| الوصف: | Esophageal cancer (ECa) remains a major cause of mortality across the globe. The expression of EIF3J-AS1 is altered in a plethora of tumors, but its role in ECa development and progression are undefined. Here, we show that EIF3J-AS1 is up-regulated in ECa and that its expression correlates with advanced TNM stage (P = 0.014), invasion depth (P = 0.001), positive lymph node metastasis (P |
| اللغة: | English |
| تدمد: | 2045-2322 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46351d1ec347667b1ce34b0d6c31cd69 https://doaj.org/article/f63b89f3464941ad8f325f91ecc9fd23 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....46351d1ec347667b1ce34b0d6c31cd69 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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