The variety of phenotypes behind ‘double outlet right ventricle’: clinical and imaging presentations in four dogs and a cat
| العنوان: | The variety of phenotypes behind ‘double outlet right ventricle’: clinical and imaging presentations in four dogs and a cat |
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| المؤلفون: | Charlotte Misbach, Andrés Pun-García, Emilie Trehiou-Sechi, Marine Roche-Catholy, Valérie Chetboul, Camille Poissonnier, Peggy Passavin, Vittorio Saponaro, Alexis Morlet, Nicolas Borenstein |
| المساهمون: | Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Centre Hospitalier Universitaire Vétérinaire d'Alfort [Maison Alfort] (CHUVA), École nationale vétérinaire d'Alfort (ENVA)-PRES Université Paris-Est, Institut Mutualiste de Montsouris (IMM), École nationale vétérinaire - Alfort (ENVA)-PRES Université Paris-Est, CCSD, Accord Elsevier |
| المصدر: | Journal of Veterinary Cardiology Journal of Veterinary Cardiology, Elsevier, 2020, 31, pp.51-60. ⟨10.1016/j.jvc.2020.08.005⟩ |
| بيانات النشر: | HAL CCSD, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, 040301 veterinary sciences, Physiology, [SDV]Life Sciences [q-bio], Exercise intolerance, 030204 cardiovascular system & hematology, Tachypnea, Canine, 0403 veterinary science, Feline, 03 medical and health sciences, Lethargy, Congenital, 0302 clinical medicine, Right ventricular hypertrophy, Double outlet right ventricle, Ductus arteriosus, Internal medicine, medicine, cardiovascular diseases, General Veterinary, business.industry, Doppler, Heart, 04 agricultural and veterinary sciences, medicine.disease, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, Ventricle, Cardiology, cardiovascular system, Subvalvular Aortic Stenosis, medicine.symptom, business |
| الوصف: | International audience; This report describes five cases of double outlet right ventricle (DORV) in four dogs (aged 3-18 months, two males and two females) and a domestic shorthair cat (aged 6 months, female) who presented with various clinical signs including tachypnea (n = 5), exercise intolerance (n = 5), mucous cyanosis (n = 3), delayed growth (n = 2), and/or lethargy (n = 2). The represented canine breeds were poodle, Yorkshire terrier, Samoyed, and Shetland sheepdog. For all animals, echocardiography revealed marked aortic dextroposition with both arterial trunks totally arising from the right ventricle, associated with a ventricular septal defect and various other congenital abnormalities, including subvalvular aortic stenosis (n = 2), minor aortic insufficiency (n = 5), subvalvular pulmonic stenosis with pulmonary trunk hypoplasia (n = 1), patent ductus arteriosus (n = 1), minor mitral and/or tricuspid dysplasia (n = 3). Subsequent cardiac remodeling was characterized by marked right ventricular hypertrophy for all patients, associated with right ventricular and right atrial dilation for most of them (4/5). Two dogs died soon after the initial DORV diagnosis (i.e. after 24 h and two months). A surgical correction attempted for another dog confirmed the presence of a DORV associated with patent ductus arteriosus, but the animal died during the procedure from sudden cardiac arrest. The fourth dog underwent a contrast-enhanced retrospective electrocardiogram-gated multidetector computed tomography angiography under general anesthesia, which confirmed the conotruncal malformation. Despite episodes of exercise intolerance, this dog is still alive, at the age of 53 months, as is the cat at the age of 21 months. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1760-2734 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f4bf86e82b55acd8d35f311feddf66 https://hal.archives-ouvertes.fr/hal-03492483 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....46f4bf86e82b55acd8d35f311feddf66 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17602734 |
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