Thirty-Year Time Trends in Diabetic Retinopathy and Macular Edema in Youth With Type 1 Diabetes
| العنوان: | Thirty-Year Time Trends in Diabetic Retinopathy and Macular Edema in Youth With Type 1 Diabetes |
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| المؤلفون: | Digby W. Allen, Gerald Liew, Yoon Hi Cho, Alison Pryke, Janine Cusumano, Stephen Hing, Albert K. Chan, Maria E. Craig, Kim C. Donaghue |
| المصدر: | Diabetes Care. 45:2247-2254 |
| بيانات النشر: | American Diabetes Association, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Glycated Hemoglobin, Male, Advanced and Specialized Nursing, Diabetic Retinopathy, Adolescent, Endocrinology, Diabetes and Metabolism, Overweight, Macular Edema, Cholesterol, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Risk Factors, Internal Medicine, Humans, Insulin, Female, Obesity |
| الوصف: | OBJECTIVE To examine trends in diabetic retinopathy (DR) and diabetic macular edema (DME) in adolescents with type 1 diabetes between 1990 and 2019. RESEARCH DESIGN AND METHODS We analyzed 5,487 complication assessments for 2,404 adolescents (52.7% female, aged 12–20 years, diabetes duration >5 years), stratified by three decades (1990–1999, 2000–2009, 2010–2019). DR and DME were graded according to the modified Airlie House classification from seven-field stereoscopic fundal photography. RESULTS Over three decades, the prevalence of DR was 40, 21, and 20% (P < 0.001) and DME 1.4, 0.5, and 0.9% (P = 0.13), respectively, for 1990–1999, 2000–2009, and 2010–2019. Continuous subcutaneous insulin infusion (CSII) use increased (0, 12, and 55%; P < 0.001); mean HbA1c was bimodal (8.7, 8.5, and 8.7%; P < 0.001), and the proportion of adolescents meeting target HbA1c CONCLUSIONS One in five adolescents with type 1 diabetes had DR in the last decade. These findings support contemporary guidelines for lower glycemic targets, increasing CSII use, and targeting modifiable risk factors including blood pressure, cholesterol, and overweight/obesity. |
| تدمد: | 1935-5548 0149-5992 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471a3c7f097dd21556962f09ce95b3f3 https://doi.org/10.2337/dc21-1652 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....471a3c7f097dd21556962f09ce95b3f3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19355548 01495992 |
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