Different responses of the oral, nasal and lung microbiomes to cigarette smoke
| العنوان: | Different responses of the oral, nasal and lung microbiomes to cigarette smoke |
|---|---|
| المؤلفون: | Draginja Kovacevic, Karoline I. Gaede, Stefan Pfeiffer, Christian Herzmann, Michael Schloter, Susanne Krauss-Etschmann |
| المصدر: | Thorax Thorax 8, DOI: 10.1136/thoraxjnl-2020-216153 (2021) |
| بيانات النشر: | BMJ, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, Physiology, Brief Communication, Tobacco And The Lung, Cigarette smoking, Smoke, Cigarette smoke, Medicine, Humans, Clinical significance, Microbiome, Prospective Studies, Prospective cohort study, Lung, Health needs, business.industry, Microbiota, Smoking, tobacco and the lung, ddc, medicine.anatomical_structure, business, Respiratory tract |
| الوصف: | To examine the role of smoking on the bacterial community composition of the upper and the lower respiratory tract, a monocentric, controlled prospective study was performed, including healthy smokers, ex-smokers and never-smokers. Smokers were further grouped according to their smoking history. Bacterial diversity was analysed using a molecular barcoding approach based on directly extracted DNA. Our study shows for the first time distinct bacterial response patterns in the upper and lower respiratory tract to cigarette smoking leading to a higher abundance of opportunistic pathogens. The clinical significance of these dysbioses for health needs to be further explored. |
| وصف الملف: | application/pdf |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486b0cbcbe3b8c30de3c58fa7e302a75 https://mediatum.ub.tum.de/1638499 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....486b0cbcbe3b8c30de3c58fa7e302a75 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |