Characteristics and prognostic factors of COVID-19 among infected cases: a nationwide Tunisian analysis
| العنوان: | Characteristics and prognostic factors of COVID-19 among infected cases: a nationwide Tunisian analysis |
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| المؤلفون: | Ines Cherif, Nourhene Najar, Salma Abid, Gharbi D, Chahida Harizi, M.K. Chahed, Hamida Ben Salah, Molka Osman, Leila Bouabid, Souha Bougatef, Nissaf Bouafif Ben-Alaya, H Letaief, Radhouane Fakhfakh, Rym Mallekh, Ilhem Boutiba-Ben Boubaker, Ilhem Bouaziz, Yosr Ayedi, Aicha Hchaichi, Mouna Safer, Sonia Dhaouadi, Sondes Derouiche, Oumaima Ben Ayed |
| المصدر: | BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021) BMC Infectious Diseases |
| بيانات النشر: | BMC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Tunisia, Adolescent, SARS CoV-2, Disease, Prognostic factors, 01 natural sciences, law.invention, Disease Outbreaks, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, Young Adult, 0302 clinical medicine, law, Internal medicine, Medicine, Humans, lcsh:RC109-216, 030212 general & internal medicine, 0101 mathematics, Young adult, Child, Survival rate, Aged, Proportional Hazards Models, Retrospective Studies, Clinical characteristics, Proportional hazards model, business.industry, SARS-CoV-2, 010102 general mathematics, Age Factors, Outbreak, COVID-19, Retrospective cohort study, Middle Aged, Prognosis, Intensive care unit, Hospitalization, Survival Rate, Infectious Diseases, Cohort, RNA, Viral, Female, business, Research Article |
| الوصف: | Background The outbreak of coronavirus disease (COVID-19) continues to constitute an international public health concern. Few data are available on the duration and prognostic factors of the disease. We aimed to study the recovery time among a Tunisian cohort of COVID-19 confirmed patients and identify the prognostic factors. Methods A retrospective, nationwide study was conducted from March 2 to May 8, 2020, recruiting all patients who were diagnosed with COVID-19, by RT-PCR methods, in Tunisia. Data were collected via phone call interview. Kaplan-Meir Methods and Cox proportional hazards regression models were, respectively, used to study the recovery time and estimate its prognostic factors. Results One thousand and thirty patients with COVID-19 (aged 43.2 ± 18.2 years, 526 female (51.1%)) were enrolled. Among them 141 (14.8%) were healthcare professionals. Out of 173 patients (17.8%) admitted to the hospital, 47 were admitted in an intensive care unit. Among 827 patients who didn’t require specialized care, 55.5% were self-isolated at home, while the rest were in specialized centers. Six hundred and two patients were symptomatic. A total of 634 (61.6%) patients have recovered and 45 (4.4%) patients died. The median duration of illness was estimated to be 31 days (95% CI: [29–32]). Older age (HR = 0.66, CI:[0.46–0.96], P = 0.031) and symptoms (HR = 0.61, CI:[0.43–0.81], P = 0.021) were independently associated with a delay in recovery time. Being a healthcare professional (HR = 1.52, CI: [1.10–2.08], P = 0.011) and patients in home isolation compared to isolation centers (HR = 2.99, CI: [1.85–4.83], P 3) were independently associated with faster recovery time. Conclusion The duration of illness was estimated to be 1 month. However, this long estimated duration of illness may not equate to infectiousness. A particular attention must to be paid to elderly and symptomatic patients with closer monitoring. |
| اللغة: | English |
| تدمد: | 1471-2334 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48acba0ecbd5038963749537f6c1ca00 https://doaj.org/article/57843fecf9a147b4acdbb7f27797c328 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....48acba0ecbd5038963749537f6c1ca00 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14712334 |
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