Off-pump myocardial revascularization attenuates endothelin-1 expression in systemic, pulmonary, and coronary circulation
| العنوان: | Off-pump myocardial revascularization attenuates endothelin-1 expression in systemic, pulmonary, and coronary circulation |
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| المؤلفون: | Kristina Brkić, Davor Barić, Dubravka Jonjić, Mislav Planinc, Igor Rudež, Daniel Unić, Željko Sutlić |
| المصدر: | Wiener klinische Wochenschrift. 126:710-717 |
| بيانات النشر: | Springer Science and Business Media LLC, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Male, Pulmonary Circulation, medicine.medical_specialty, Myocardial revascularization, medicine.medical_treatment, Coronary Artery Bypass, Off-Pump, Coronary Artery Disease, Pulmonary Artery, Revascularization, law.invention, Coronary circulation, Randomized controlled trial, law, Coronary Circulation, Internal medicine, Myocardial Revascularization, Cardiopulmonary bypass, Humans, Medicine, In patient, Coronary sinus, Endothelin-1, business.industry, Troponin I, General Medicine, Middle Aged, Coronary Vessels, Endothelin 1, Treatment Outcome, medicine.anatomical_structure, Cardiology, Female, business, Biomarkers |
| الوصف: | The objective of this study was to evaluate the influence of cardiopulmonary bypass (CPB) on endothelin-1 (ET-1) expression in various circulation compartments in patients undergoing myocardial revascularization. A total of 30 patients were randomized to undergo myocardial revascularization with (CABG, n = 15) or without (OPCAB, n = 15) CPB. Samples were taken preoperatively, after establishing CPB and after CPB (CABG group), prior to and after revascularization (OPCAB group), and 6 and 24 h postoperatively. Values of ET-1 were compared between groups at all time points and correlated with postoperative cardioselective enzyme values and clinical parameters. In OPCAB group, ET-1 levels did not significantly vary between time points. In CABG group, ET-1 levels were significantly elevated vs. baseline in arterial: ART-T2 vs. ART-T0 (1.83 ± 1.81 vs. 0.76 ± 1.07 fmol/mL, p = 0.05), pulmonary: SG-T2 vs. SG-T0 (2.70 ± 2.75 vs. 0.39 ± 0.28 fmol/mL, p |
| تدمد: | 1613-7671 0043-5325 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f84e69f5d176a37937493bcd656c2d https://doi.org/10.1007/s00508-014-0664-8 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....48f84e69f5d176a37937493bcd656c2d |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 16137671 00435325 |
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