Comparison of visualization tools for single-cell RNAseq data

التفاصيل البيبلوغرافية
العنوان: Comparison of visualization tools for single-cell RNAseq data
المؤلفون: Batuhan Cakir, Ni Huang, Pınar Pir, Stijn van Dongen, Martin Prete, Vladimir Yu. Kiselev
المصدر: Nar Genomics and Bioinformatics
بيانات النشر: Oxford University Press (OUP), 2020.
سنة النشر: 2020
مصطلحات موضوعية: AcademicSubjects/SCI01140, 0303 health sciences, Information retrieval, AcademicSubjects/SCI01060, business.industry, Computer science, AcademicSubjects/SCI00030, AcademicSubjects/SCI01180, Interactive analysis, Methods and Benchm, Visualization, 03 medical and health sciences, R package, 0302 clinical medicine, User experience design, Data format, AcademicSubjects/SCI00980, High dimensionality, business, Knowledge transfer, 030217 neurology & neurosurgery, 030304 developmental biology
الوصف: In the last decade, single cell RNAseq (scRNAseq) datasets have grown in size from a single cell to millions of cells. Due to its high dimensionality, it is not always feasible to visualize scRNAseq data and share it in a scientific report or an article publication format. Recently, many interactive analysis and visualization tools have been developed to address this issue and facilitate knowledge transfer in the scientific community. In this study, we review several of the currently available scRNAseq visualization tools and benchmark the subset that allows to visualize the data on the web and share it with others. We consider the memory and time required to prepare datasets for sharing as the number of cells increases, and additionally review the user experience and features available in the web interface. To address the problem of format compatibility we have also developed a user-friendly R package, sceasy, which allows users to convert their own scRNAseq datasets into a specific data format for visualization.
تدمد: 2631-9268
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49741d92bad5742e905304a1e0ac49d2
https://doi.org/10.1093/nargab/lqaa052
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....49741d92bad5742e905304a1e0ac49d2
قاعدة البيانات: OpenAIRE