Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide

التفاصيل البيبلوغرافية
العنوان: Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide
المؤلفون: Vittore Verratti, Suwas Bhandari, Danilo Bondi
المصدر: Physiological Reports
Physiological Reports, Vol 8, Iss 16, Pp n/a-n/a (2020)
بيانات النشر: John Wiley and Sons Inc., 2020.
سنة النشر: 2020
مصطلحات موضوعية: medicine.medical_specialty, Ambulatory blood pressure, breathing, Physiology, Case Report, 030204 cardiovascular system & hematology, Nocturnal, lcsh:Physiology, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Internal medicine, medicine, sleep, Oxygen saturation (medicine), lcsh:QP1-981, Himalayas, business.industry, Sleep apnea, blood pressure, Cardiorespiratory fitness, Hypoxia (medical), Effects of high altitude on humans, medicine.disease, hypobaric hypoxia, Blood pressure, Cardiology, medicine.symptom, business, 030217 neurology & neurosurgery, physiological monitoring
الوصف: The cardiopulmonary system is a physiological cornerstone in the adaptive response to hypobaric hypoxia. Portable devices make it feasible nowadays to precisely assess the response to high altitude (HA) expeditions. In this study, we investigated breathing and arterial blood pressure responses during a Himalayan trek from 665 m to 4,780 m altitude in a white European (Italian) sojourner and a native Nepali (Tamang) guide, both healthy males. Resting diurnal and nocturnal data were acquired by means of ambulatory blood pressure monitoring (ABPM) and sleep apnea monitoring. We found an increase in the mean diurnal arterial blood pressure. Nocturnal blood pressure dipping was confirmed at all altitudes. Oxygen saturation decreased at altitude, with its additional nocturnal fall. Sleep apneic episodes, present in the Italian only, increased with altitude. We conclude that the nocturnal, more than diurnal, cardiorespiratory function is affected by HA hypoxia. Further studies should address the role of ethnicity, medications, and sociodemographic factors in the cardiorespiratory responses to hypobaric hypoxia.
In this study, we investigated cardiopulmonary nocturnal and diurnal responses during a Himalayan trek in a white European (Italian) sojourner and a native Nepali (Tamang) guide, by means of ambulatory blood pressure and sleep‐apnea monitoring. We found an increase in the mean BP. Oxygen saturation decreased at altitude, with its additional nocturnal fall. Sleep apneic episodes increased with altitude.
اللغة: English
تدمد: 2051-817X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497511f80db24fa98abc95c5db3da44b
http://europepmc.org/articles/PMC7435026
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....497511f80db24fa98abc95c5db3da44b
قاعدة البيانات: OpenAIRE